Karlsruhe's 2025 population is now estimated at 323,804. In 1950, the population of Karlsruhe was 198,682. Karlsruhe has grown by 748 in the last year, which represents a 0.23% annual change.These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Karlsruhe, which typically includes Karlsruhe's population in addition to adjacent suburban areas.