12 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Fort Deposit | 1 | 1,095 | 1,233 | -2.41% | 193 | 6 | Town |
| Fort Deposit | 2 | 1,095 | 1,227 | -2.41% | 193 | 6 | Town |
| Mosses | 3 | 758 | 834 | -1.94% | 160 | 5 | Town |
| Mosses | 4 | 758 | 832 | -1.94% | 160 | 5 | Town |
| White Hall | 5 | 737 | 808 | -1.86% | 48 | 15 | Town |
| White Hall | 6 | 737 | 806 | -1.86% | 48 | 15 | Town |
| Hayneville | 7 | 725 | 835 | -2.95% | 390 | 2 | Town |
| Hayneville | 8 | 725 | 832 | -2.95% | 390 | 2 | Town |
| Gordonville | 9 | 219 | 244 | -2.23% | 40 | 6 | Town |
| Gordonville | 10 | 219 | 243 | -2.23% | 40 | 6 | Town |
| Lowndesboro | 11 | 73 | 87 | -3.95% | 92 | 1 | Town |
| Lowndesboro | 12 | 73 | 87 | -3.95% | 92 | 1 | Town |
Fort Deposit is the largest city in Lowndes County, with a population of 1,095.
Lowndesboro is the smallest city in Lowndes County, with a population of 73.
There are 12 cities in Lowndes County, Alabama.