15 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Ozark | 1 | 3,616 | 3,535 | 0.42% | 456 | 8 | City |
| Ozark | 2 | 3,616 | 3,540 | 0.42% | 456 | 8 | City |
| Charleston | 3 | 2,765 | 2,586 | 1.24% | 721 | 4 | City |
| Charleston | 4 | 2,765 | 2,593 | 1.24% | 721 | 4 | City |
| Altus | 5 | 675 | 667 | 0.15% | 357 | 2 | City |
| Altus | 6 | 675 | 668 | 0.15% | 357 | 2 | City |
| Branch | 7 | 308 | 300 | 0.33% | 99 | 3 | City |
| Branch | 8 | 308 | 301 | 0.33% | 99 | 3 | City |
| Denning | 9 | 207 | 199 | 0.49% | 192 | 1 | Town |
| Denning | 10 | 207 | 199 | 0.49% | 192 | 1 | Town |
| Caulksville | 11 | 163 | 158 | 0.62% | 121 | 1 | Town |
| Caulksville | 12 | 163 | 158 | 0.62% | 121 | 1 | Town |
| Alix | 13 | 91 | 77 | 7.06% | 189 | 0 | CDP |
| Wiederkehr Village | 14 | 49 | 48 | 0% | 12 | 4 | City |
| Wiederkehr Village | 15 | 49 | 48 | 0% | 12 | 4 | City |
Ozark is the largest city in Franklin County, with a population of 3,616.
Wiederkehr Village is the smallest city in Franklin County, with a population of 49.
There are 15 cities in Franklin County, Arkansas.