11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Hope | 1 | 8,326 | 8,905 | -1.37% | 779 | 10.68 | City |
| Blevins | 2 | 271 | 285 | -1.09% | 273 | 0.99 | City |
| Perrytown | 3 | 221 | 231 | -0.9% | 159 | 1.39 | Town |
| Fulton | 4 | 109 | 113 | -0.91% | 612 | 0.18 | Town |
| Center Point | 5 | 102 | 100 | 6.25% | 60 | 1.70 | CDP |
| Washington | 6 | 88 | 93 | -1.12% | 87 | 1.01 | City |
| Oakhaven | 7 | 64 | 69 | -1.54% | 1,391 | 0.05 | Town |
| McCaskill | 8 | 56 | 56 | 0% | 76 | 0.74 | Town |
| Patmos | 9 | 53 | 57 | -1.85% | 477 | 0.11 | Town |
| Ozan | 10 | 47 | 51 | -2.08% | 144 | 0.33 | Town |
| McNab | 11 | 28 | 30 | 0% | 82 | 0.34 | Town |
Hope is the largest city in Hempstead County, with a population of 8,326.
McNab is the smallest city in Hempstead County.
There are 11 cities in Hempstead County, Arkansas.