18 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Sarasota | 1 | 59,211 | 55,188 | 1.38% | 4,027 | 14.70 | City |
| Bradenton | 2 | 57,916 | 55,815 | 0.73% | 4,039 | 14.34 | City |
| Lakewood Ranch | 3 | 42,932 | 26,513 | 7.14% | 932 | 46.08 | CDP |
| South Bradenton | 4 | 26,294 | 24,885 | 1.05% | 5,843 | 4.50 | CDP |
| Bayshore Gardens | 5 | 19,350 | 20,380 | 1.05% | 5,513 | 3.51 | CDP |
| Palmetto | 6 | 13,743 | 13,327 | 0.61% | 2,561 | 5.37 | City |
| Memphis | 7 | 11,692 | 10,702 | 2.24% | 3,595 | 3.25 | CDP |
| Longboat Key | 8 | 7,479 | 7,501 | -0.05% | 1,834 | 4.08 | Town |
| West Samoset | 9 | 7,335 | 7,191 | 1.61% | 5,445 | 1.35 | CDP |
| Ellenton | 10 | 5,670 | 5,754 | 1.67% | 1,715 | 3.31 | CDP |
| Whitfield | 11 | 5,590 | 4,398 | 3.35% | 4,054 | 1.38 | CDP |
| Cortez | 12 | 5,231 | 5,088 | 1.28% | 2,345 | 2.23 | CDP |
| Samoset | 13 | 4,330 | 4,701 | 0.74% | 2,942 | 1.47 | CDP |
| West Bradenton | 14 | 3,871 | 3,735 | -0.54% | 2,975 | 1.30 | CDP |
| Holmes Beach | 15 | 3,037 | 3,011 | 0.16% | 1,810 | 1.68 | City |
| Old Miakka | 16 | 1,972 | 1,486 | 7.12% | 162 | 12.18 | CDP |
| Anna Maria | 17 | 1,033 | 970 | 1.27% | 1,405 | 0.73 | City |
| Bradenton Beach | 18 | 922 | 907 | 0.33% | 1,783 | 0.52 | City |
Sarasota is the largest city in Manatee County, with a population of 59,211.
Bradenton Beach is the smallest city in Manatee County.
There are 18 cities in Manatee County, Florida.