15 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Waynesboro | 1 | 5,497 | 5,787 | -1.04% | 1,005 | 5 | City |
| Waynesboro | 2 | 5,497 | 5,787 | -1.04% | 1,005 | 5 | City |
| Sardis | 3 | 1,009 | 996 | 0.2% | 652 | 2 | City |
| Sardis | 4 | 1,009 | 998 | 0.2% | 652 | 2 | City |
| Midville | 5 | 379 | 386 | -0.52% | 190 | 2 | City |
| Midville | 6 | 379 | 386 | -0.52% | 190 | 2 | City |
| Keysville | 7 | 320 | 301 | 0.95% | 304 | 1 | City |
| Keysville | 8 | 320 | 303 | 0.95% | 304 | 1 | City |
| Girard | 9 | 184 | 183 | 0% | 58 | 3 | Town |
| Girard | 10 | 184 | 183 | 0% | 58 | 3 | Town |
| Gough | 11 | 144 | 158 | 7.46% | 171 | 1 | CDP |
| Summertown | 12 | 119 | 119 | 0% | 151 | 1 | City |
| Summertown | 13 | 119 | 119 | 0% | 151 | 1 | City |
| Vidette | 14 | 102 | 104 | -0.97% | 105 | 1 | City |
| Vidette | 15 | 102 | 104 | -0.97% | 105 | 1 | City |
Waynesboro is the largest city in Burke County, with a population of 5,497.
Vidette is the smallest city in Burke County, with a population of 102.
There are 15 cities in Burke County, Georgia.