11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Greensboro | 1 | 3,560 | 3,642 | -0.36% | 515 | 7 | City |
| Greensboro | 2 | 3,560 | 3,625 | -0.36% | 515 | 7 | City |
| Union Point | 3 | 1,883 | 1,603 | 2.9% | 955 | 2 | City |
| Union Point | 4 | 1,883 | 1,615 | 2.9% | 955 | 2 | City |
| Woodville | 5 | 314 | 265 | 2.95% | 63 | 5 | City |
| Woodville | 6 | 314 | 268 | 2.95% | 63 | 5 | City |
| White Plains | 7 | 284 | 242 | 2.9% | 55 | 5 | City |
| White Plains | 8 | 284 | 243 | 2.9% | 55 | 5 | City |
| Siloam | 9 | 189 | 192 | -0.53% | 156 | 1 | Town |
| Siloam | 10 | 189 | 191 | -0.53% | 156 | 1 | Town |
| Godfrey | 11 | 166 | 125 | 7.1% | 156 | 1 | CDP |
Greensboro is the largest city in Greene County, with a population of 3,560.
Godfrey is the smallest city in Greene County, with a population of 166.
There are 11 cities in Greene County, Georgia.