4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Jeffersonville | 1 | 914 | 976 | -1.3% | 250 | 4 | City |
| Jeffersonville | 2 | 914 | 974 | -1.3% | 250 | 4 | City |
| Danville | 3 | 157 | 169 | -1.88% | 199 | 1 | Town |
| Danville | 4 | 157 | 169 | -1.88% | 199 | 1 | Town |
Jeffersonville is the largest city in Twiggs County, with a population of 914.
Danville is the smallest city in Twiggs County, with a population of 157.
There are 4 cities in Twiggs County, Georgia.