18 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Jeffersonville | 1 | 65,273 | 61,563 | 1.77% | 2,455 | 27 | Township |
| Jeffersonville | 2 | 53,746 | 49,573 | 1.58% | 1,577 | 34 | City |
| Clarksville | 3 | 21,970 | 22,323 | -0.32% | 2,188 | 10 | Town |
| Charlestown | 4 | 16,465 | 15,227 | 1.1% | 255 | 65 | Township |
| Silver Creek | 5 | 14,457 | 13,830 | -0.01% | 867 | 17 | Township |
| Sellersburg | 6 | 10,226 | 9,378 | 1.68% | 1,380 | 7 | Town |
| Utica | 7 | 9,250 | 8,184 | 2.41% | 429 | 22 | Township |
| Charlestown | 8 | 8,737 | 7,844 | 2.08% | 763 | 11 | City |
| Carr | 9 | 5,144 | 4,853 | 0.82% | 195 | 26 | Township |
| Union | 10 | 4,794 | 4,548 | 1.2% | 230 | 21 | Township |
| Wood | 11 | 2,924 | 2,777 | 1.21% | 75 | 39 | Township |
| Oregon | 12 | 1,842 | 1,737 | 1.26% | 59 | 31 | Township |
| Utica | 13 | 1,345 | 890 | 7.26% | 1,129 | 1 | Town |
| New Pekin | 14 | 1,334 | 1,327 | 0.08% | 560 | 2 | Town |
| Owen | 15 | 1,002 | 946 | 1.42% | 59 | 17 | Township |
| Borden | 16 | 824 | 783 | 0.98% | 592 | 1 | Town |
| Bethlehem | 17 | 718 | 729 | -0.69% | 20 | 35 | Township |
| Bethlehem | 18 | 380 | 363 | 0.8% | 21 | 18 | Township |
Jeffersonville is the largest city in Clark County, with a population of 65,273.
Bethlehem is the smallest city in Clark County, with a population of 380.
There are 18 cities in Clark County, Indiana.