16 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Cherokee | 1 | 5,183 | 5,196 | -0.06% | 759 | 7 | City |
| Cherokee | 2 | 5,183 | 5,195 | -0.06% | 759 | 7 | City |
| Marcus | 3 | 1,067 | 1,074 | -0.19% | 698 | 2 | City |
| Marcus | 4 | 1,067 | 1,076 | -0.19% | 698 | 2 | City |
| Aurelia | 5 | 970 | 968 | 0% | 957 | 1 | City |
| Aurelia | 6 | 970 | 968 | 0% | 957 | 1 | City |
| Quimby | 7 | 244 | 246 | -0.41% | 600 | 0 | City |
| Quimby | 8 | 244 | 246 | -0.41% | 600 | 0 | City |
| Cleghorn | 9 | 234 | 237 | -0.43% | 1,026 | 0 | City |
| Cleghorn | 10 | 234 | 237 | -0.43% | 1,026 | 0 | City |
| Washta | 11 | 205 | 208 | -0.49% | 203 | 1 | City |
| Washta | 12 | 205 | 208 | -0.49% | 203 | 1 | City |
| Meriden | 13 | 175 | 173 | 0% | 1,549 | 0 | City |
| Meriden | 14 | 175 | 173 | 0% | 1,549 | 0 | City |
| Larrabee | 15 | 116 | 116 | 0% | 892 | 0 | City |
| Larrabee | 16 | 116 | 116 | 0% | 892 | 0 | City |
Cherokee is the largest city in Cherokee County, with a population of 5,183.
Larrabee is the smallest city in Cherokee County, with a population of 116.
There are 16 cities in Cherokee County, Iowa.