30 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Springfield | 1 | 156,224 | 155,258 | 0.43% | 4,902 | 32 | City |
| Springfield | 2 | 154,703 | 155,258 | -0.06% | 4,854 | 32 | City |
| Chicopee | 3 | 55,449 | 55,444 | 0.06% | 2,421 | 23 | City |
| Chicopee | 4 | 55,349 | 55,444 | -0.03% | 2,416 | 23 | City |
| Westfield | 5 | 40,643 | 40,169 | 0.3% | 879 | 46 | City |
| Westfield | 6 | 40,520 | 40,169 | 0.15% | 876 | 46 | City |
| Holyoke | 7 | 38,168 | 38,139 | 0.43% | 1,803 | 21 | City |
| Holyoke | 8 | 37,687 | 38,139 | -0.2% | 1,780 | 21 | City |
| Agawam Town | 9 | 29,339 | 28,627 | 1.02% | 1,258 | 23 | City |
| West Springfield Town | 10 | 29,226 | 28,767 | 0.34% | 1,747 | 17 | City |
| West Springfield Town | 11 | 29,158 | 28,767 | 0.22% | 1,743 | 17 | City |
| Agawam Town | 12 | 28,810 | 28,627 | 0.11% | 1,235 | 23 | City |
| Ludlow | 13 | 21,538 | 20,763 | 0.98% | 792 | 27 | Town |
| East Longmeadow | 14 | 16,657 | 16,408 | 0.43% | 1,288 | 13 | Town |
| Longmeadow | 15 | 15,796 | 15,813 | 0.27% | 1,738 | 9 | Town |
| Wilbraham | 16 | 14,851 | 14,584 | 0.64% | 674 | 22 | Town |
| Palmer Town | 17 | 12,480 | 12,419 | 0.37% | 395 | 32 | City |
| Palmer Town | 18 | 12,372 | 12,419 | -0.06% | 392 | 32 | City |
| Southwick | 19 | 9,387 | 9,217 | 0.59% | 305 | 31 | Town |
| Monson | 20 | 8,234 | 8,133 | 0.43% | 186 | 44 | Town |
| Hampden | 21 | 5,004 | 4,956 | 0.4% | 255 | 20 | Town |
| Brimfield | 22 | 3,781 | 3,689 | 0.64% | 109 | 35 | Town |
| Holland | 23 | 2,595 | 2,596 | 0.27% | 211 | 12 | Town |
| Wales | 24 | 1,842 | 1,830 | 0.38% | 117 | 16 | Town |
| Russell | 25 | 1,650 | 1,639 | 0.3% | 94 | 17 | Town |
| Granville | 26 | 1,554 | 1,538 | 0.45% | 37 | 42 | Town |
| Chester | 27 | 1,233 | 1,225 | 0.49% | 34 | 37 | Town |
| Blandford | 28 | 1,215 | 1,211 | 0.25% | 24 | 52 | Town |
| Montgomery | 29 | 851 | 819 | 0.83% | 57 | 15 | Town |
| Tolland | 30 | 480 | 470 | 0.63% | 15 | 32 | Town |
Springfield is the largest city in Hampden County, with a population of 156,224.
Tolland is the smallest city in Hampden County, with a population of 480.
There are 30 cities in Hampden County, Massachusetts.