Mayesville is a city located in South Carolina. With a 2020 population of 710, it is the 174th largest city in South Carolina and the 11816th largest city in the United States. Mayesville is currently declining at a rate of -0.56% annually and its population has decreased by -2.87% since the most recent census, which recorded a population of 731 in 2010. Mayesville reached it's highest population of 729 in 2010. Spanning over 1 miles, Mayesville has a population density of 693 people per square mile.
The average household income in Mayesville is $57,149 with a poverty rate of 23.14%. The median rental costs in recent years comes to $675 per month, and the median house value is $81,100. The median age in Mayesville is 45.5 years, 37.5 years for males, and 50.8 years for females. For every 100 females there are 65.5 males.