8 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Boonville | 1 | 8,001 | 7,586 | 0.87% | 966 | 8 | City |
| Pilot Grove | 2 | 703 | 664 | 1.01% | 1,670 | 0 | City |
| Otterville | 3 | 453 | 441 | 0.44% | 926 | 0 | City |
| Windsor Place | 4 | 365 | 353 | 0.55% | 407 | 1 | Village |
| Bunceton | 5 | 340 | 333 | 0.29% | 360 | 1 | City |
| Prairie Home | 6 | 268 | 262 | 0.37% | 691 | 0 | City |
| Blackwater | 7 | 180 | 174 | 0.56% | 549 | 0 | City |
| Wooldridge | 8 | 31 | 30 | 0% | 517 | 0 | Village |
Boonville is the largest city in Cooper County, with a population of 8,001.
Wooldridge is the smallest city in Cooper County, with a population of 31.
There are 8 cities in Cooper County, Missouri.