New Madrid County, Missouri Cities (2025)

15 cities

City
Rank
2025 Pop.
2020 Pop.
Annual Change
Density
Area (mi²)
Type
Portageville12,6572,924-1.96%1,3022.04 City
New Madrid22,5262,768-1.86%5614.50 City
Lilbourn3888990-2.2%9390.95 City
Gideon4696775-2.25%3891.79 City
Morehouse5667739-2.06%8300.80 City
Parma6496553-2.17%7770.64 City
Matthews7490530-1.61%2501.96 City
Marston8356391-1.93%3221.10 City
Risco9253283-2.32%4520.56 City
Howardville10247274-1.98%1,0830.23 City
Canalou11145157-1.36%7180.20 City
Tallapoosa127079-2.78%1570.45 City
Catron1337390%990.37 Town
Hayward142779-20.59%1070.25 CDP
North Lilbourn1520220%1160.17 Village

New Madrid County Cities Summary

Largest City

Portageville is the largest city in New Madrid County, with a population of 2,657.

Smallest City

North Lilbourn is the smallest city in New Madrid County, with a population of 20.

10 Largest Cities

There are 15 cities in New Madrid County, Missouri.

Location of New Madrid County