11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Unionville | 1 | 1,695 | 1,730 | -0.41% | 849 | 2 | City |
| Wilson | 2 | 545 | 556 | -0.37% | 15 | 36.23 | Township |
| Elm | 3 | 513 | 522 | -0.58% | 7 | 78.16 | Township |
| York | 4 | 183 | 187 | -0.54% | 3 | 67.72 | Township |
| Grant | 5 | 175 | 178 | -0.57% | 8 | 23.12 | Township |
| Medicine | 6 | 142 | 145 | -0.7% | 3 | 54.31 | Township |
| Sherman | 7 | 129 | 132 | -0.77% | 3 | 40.02 | Township |
| Worthington | 8 | 59 | 61 | 0% | 468 | 0.13 | Village |
| Lucerne | 9 | 56 | 56 | 0% | 224 | 0.25 | Village |
| Livonia | 10 | 55 | 55 | 0% | 207 | 0.27 | Village |
| Powersville | 11 | 43 | 43 | 0% | 76 | 0.56 | Village |
Unionville is the largest city in Putnam County, with a population of 1,695.
Powersville is the smallest city in Putnam County, with a population of 43.
There are 11 cities in Putnam County, Missouri.