4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Doniphan | 1 | 1,782 | 1,781 | 0% | 1,295 | 1 | City |
| Naylor | 2 | 441 | 441 | 0% | 796 | 1 | City |
| Fairdealing | 3 | 345 | 459 | -5.99% | 61 | 6 | CDP |
| Oxly | 4 | 11 | 99 | -54.17% | 4 | 3 | CDP |
Doniphan is the largest city in Ripley County, with a population of 1,782.
Oxly is the smallest city in Ripley County, with a population of 11.
There are 4 cities in Ripley County, Missouri.