16 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Spencer | 1 | 520 | 566 | -2.26% | 7 | 74 | Township |
| Spencer | 2 | 371 | 403 | -1.85% | 620 | 1 | Village |
| Butte | 3 | 363 | 390 | -2.16% | 6 | 64 | Township |
| Butte | 4 | 266 | 281 | -1.12% | 566 | 0 | Village |
| Lynch | 5 | 220 | 237 | -1.79% | 5 | 41 | Township |
| Basin | 6 | 202 | 219 | -2.42% | 2 | 129 | Township |
| Lynch | 7 | 181 | 194 | -1.63% | 339 | 1 | Village |
| Bristow | 8 | 97 | 105 | -2.02% | 3 | 33 | Township |
| McCulley | 9 | 86 | 97 | -4.44% | 2 | 53 | Township |
| Morton | 10 | 84 | 94 | -3.45% | 2 | 52 | Township |
| Naper | 11 | 81 | 88 | -2.41% | 600 | 0 | Village |
| Bush | 12 | 70 | 75 | -1.41% | 1 | 55 | Township |
| Bristow | 13 | 66 | 71 | -1.49% | 405 | 0 | Village |
| Anoka | 14 | 9 | 11 | -10% | 16 | 1 | Village |
| Gross | 15 | 2 | 2 | 0% | 16 | 0 | Village |
| Monowi | 16 | 2 | 2 | 0% | 9 | 0 | Village |
Spencer is the largest city in Boyd County, with a population of 520.
Monowi is the smallest city in Boyd County, with a population of 2.
There are 16 cities in Boyd County, Nebraska.