25 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Columbus | 1 | 24,722 | 24,076 | 0.52% | 2,331 | 10.61 | City |
| Columbus township | 2 | 3,315 | 3,310 | 0.3% | 67 | 49.79 | Township |
| Granville township | 3 | 952 | 949 | 0.21% | 27 | 35.63 | Township |
| Shell Creek township | 4 | 951 | 951 | 0.42% | 27 | 35.70 | Township |
| Humphrey | 5 | 854 | 854 | 0% | 1,645 | 0.52 | City |
| Butler township | 6 | 614 | 612 | 0.33% | 20 | 31.22 | Township |
| Lost Creek township | 7 | 505 | 509 | 0.2% | 14 | 35.95 | Township |
| St. Bernard township | 8 | 503 | 501 | 0.2% | 14 | 35.58 | Township |
| Oconee township | 9 | 494 | 497 | 0.2% | 20 | 25.04 | Township |
| Humphrey township | 10 | 482 | 483 | 0.21% | 13 | 35.87 | Township |
| Bismark township | 11 | 434 | 435 | 0.46% | 12 | 35.08 | Township |
| Duncan | 12 | 387 | 387 | 0% | 827 | 0.47 | Village |
| Creston township | 13 | 367 | 370 | 0.27% | 10 | 35.82 | Township |
| Platte Center | 14 | 327 | 334 | -0.3% | 1,094 | 0.30 | Village |
| Grand Prairie township | 15 | 326 | 332 | -0.31% | 9 | 36.12 | Township |
| Lindsay | 16 | 287 | 284 | 0.35% | 605 | 0.47 | Village |
| Monroe | 17 | 286 | 293 | -0.35% | 1,467 | 0.20 | Village |
| Burrows township | 18 | 260 | 260 | 0.39% | 7 | 35.87 | Township |
| Sherman township | 19 | 223 | 227 | 0% | 6 | 35.89 | Township |
| Walker township | 20 | 196 | 204 | -1.01% | 4 | 53.50 | Township |
| Loup township | 21 | 187 | 186 | 0.54% | 4 | 42.09 | Township |
| Creston | 22 | 174 | 176 | 0% | 841 | 0.21 | Village |
| Joliet township | 23 | 127 | 128 | 0% | 4 | 35.96 | Township |
| Monroe township | 24 | 125 | 123 | 0.81% | 4 | 34.02 | Township |
| Woodville township | 25 | 124 | 122 | 0.81% | 4 | 35.37 | Township |
Columbus is the largest city in Platte County, with a population of 24,722.
Woodville township is the smallest city in Platte County.
There are 25 cities in Platte County, Nebraska.