16 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Kent | 1 | 12,884 | 12,900 | 0.18% | 318 | 41 | Town |
| Albion | 2 | 7,684 | 7,461 | 3.64% | 304 | 25 | Town |
| Ridgeway | 3 | 6,474 | 6,577 | 0.08% | 129 | 50 | Town |
| Medina | 4 | 5,887 | 6,011 | -0.42% | 1,784 | 3 | Village |
| Albion | 5 | 5,718 | 5,647 | 0.25% | 1,958 | 3 | Village |
| Shelby | 6 | 4,813 | 4,878 | -0.08% | 104 | 46 | Town |
| Murray | 7 | 4,734 | 4,806 | 0.06% | 152 | 31 | Town |
| Clarendon | 8 | 3,338 | 3,305 | 0.09% | 95 | 35 | Town |
| Gaines | 9 | 3,198 | 3,218 | 0.09% | 93 | 34 | Town |
| Carlton | 10 | 2,819 | 2,823 | 0.32% | 65 | 44 | Town |
| Kendall | 11 | 2,588 | 2,614 | 0.08% | 79 | 33 | Town |
| Yates | 12 | 2,520 | 2,557 | 0.04% | 67 | 37 | Town |
| Albion | 13 | 2,057 | 2,018 | 0.34% | 44 | 47 | Town |
| Barre | 14 | 1,814 | 1,830 | 0.22% | 33 | 55 | Town |
| Holley | 15 | 1,717 | 1,762 | -0.52% | 1,354 | 1 | Village |
| Lyndonville | 16 | 773 | 791 | -0.51% | 755 | 1 | Village |
Kent is the largest city in Orleans County, with a population of 12,884.
Lyndonville is the smallest city in Orleans County, with a population of 773.
There are 16 cities in Orleans County, New York.