22 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Arcadia | 1 | 13,484 | 13,715 | -0.31% | 259 | 52.03 | Town |
| Ontario | 2 | 10,490 | 10,455 | -0.12% | 324 | 32.41 | Town |
| Walworth | 3 | 9,476 | 9,244 | 0.86% | 280 | 33.85 | Town |
| Macedon | 4 | 9,196 | 9,266 | -0.24% | 238 | 38.68 | Town |
| Newark | 5 | 8,895 | 9,075 | -0.4% | 1,641 | 5.42 | Village |
| Sodus | 6 | 8,053 | 8,030 | 0% | 120 | 67.27 | Town |
| Palmyra | 7 | 7,291 | 7,394 | -0.42% | 218 | 33.44 | Town |
| Williamson | 8 | 6,808 | 6,849 | -0.04% | 197 | 34.64 | Town |
| Lyons | 9 | 5,500 | 5,660 | -0.61% | 147 | 37.48 | Town |
| Marion | 10 | 4,484 | 4,562 | -0.44% | 154 | 29.15 | Town |
| Galen | 11 | 4,368 | 4,410 | 0% | 73 | 59.48 | Town |
| Wolcott | 12 | 3,928 | 4,002 | -0.43% | 101 | 39.05 | Town |
| Palmyra | 13 | 3,246 | 3,318 | -0.43% | 2,410 | 1.35 | Village |
| Rose | 14 | 2,246 | 2,295 | -0.49% | 66 | 33.90 | Town |
| Clyde | 15 | 2,119 | 2,166 | -0.42% | 964 | 2.20 | Village |
| Huron | 16 | 1,843 | 1,865 | -0.16% | 47 | 39.39 | Town |
| Butler | 17 | 1,798 | 1,820 | -0.28% | 48 | 37.09 | Town |
| Sodus | 18 | 1,689 | 1,719 | -0.35% | 1,795 | 0.94 | Village |
| Savannah | 19 | 1,606 | 1,635 | -0.56% | 45 | 35.97 | Town |
| Wolcott | 20 | 1,562 | 1,599 | -0.45% | 802 | 1.95 | Village |
| Sodus Point | 21 | 833 | 822 | 0.24% | 568 | 1.47 | Village |
| Red Creek | 22 | 479 | 493 | -0.62% | 527 | 0.91 | Village |
Arcadia is the largest city in Wayne County, with a population of 13,484.
Red Creek is the smallest city in Wayne County.
There are 22 cities in Wayne County, New York.