9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Bayboro | 1 | 936 | 1,161 | -4.59% | 504 | 1.86 | Town |
| Oriental | 2 | 907 | 882 | 0.55% | 634 | 1.43 | Town |
| Alliance | 3 | 759 | 738 | 0.53% | 364 | 2.09 | Town |
| Grantsboro | 4 | 722 | 697 | 0.7% | 187 | 3.85 | Town |
| Minnesott Beach | 5 | 545 | 530 | 0.55% | 157 | 3.47 | Town |
| Arapahoe | 6 | 435 | 415 | 0.93% | 200 | 2.17 | Town |
| Vandemere | 7 | 255 | 245 | 0.79% | 168 | 1.52 | Town |
| Stonewall | 8 | 219 | 211 | 0.92% | 128 | 1.71 | Town |
| Mesic | 9 | 150 | 144 | 0.67% | 145 | 1.03 | Town |
Bayboro is the largest city in Pamlico County, with a population of 936.
Mesic is the smallest city in Pamlico County.
There are 9 cities in Pamlico County, North Carolina.