11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Woodsfield | 1 | 2,146 | 2,205 | -0.56% | 1,065 | 2.02 | Village |
| Matamoras (New Matamoras) | 2 | 679 | 703 | -0.73% | 1,951 | 0.35 | Village |
| Sardis | 3 | 344 | 629 | -3.91% | 273 | 1.26 | CDP |
| Beallsville | 4 | 343 | 352 | -0.58% | 945 | 0.36 | Village |
| Clarington | 5 | 268 | 278 | -0.74% | 234 | 1.14 | Village |
| Lewisville | 6 | 177 | 186 | -1.12% | 477 | 0.37 | Village |
| Jerusalem | 7 | 120 | 124 | -0.83% | 496 | 0.24 | Village |
| Hannibal | 8 | 118 | 295 | -14.49% | 106 | 1.11 | CDP |
| Antioch | 9 | 73 | 75 | 0% | 709 | 0.10 | Village |
| Stafford | 10 | 67 | 69 | 0% | 197 | 0.34 | Village |
| Miltonsburg | 11 | 37 | 39 | 0% | 507 | 0.07 | Village |
Woodsfield is the largest city in Monroe County, with a population of 2,146.
Miltonsburg is the smallest city in Monroe County.
There are 11 cities in Monroe County, Ohio.