17 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Circleville | 1 | 14,786 | 13,950 | 1.14% | 2,049 | 7.22 | City |
| Scioto township | 2 | 12,399 | 11,719 | 2.05% | 280 | 44.31 | Township |
| Ashville | 3 | 4,898 | 4,553 | 1.43% | 2,054 | 2.38 | Village |
| Darby township | 4 | 3,447 | 3,217 | 1.35% | 101 | 34.24 | Township |
| Commercial Point | 5 | 3,301 | 3,085 | 1.32% | 811 | 4.07 | Village |
| Washington township | 6 | 3,196 | 3,006 | 1.24% | 135 | 23.73 | Township |
| Walnut township | 7 | 3,150 | 2,954 | 1.29% | 77 | 40.65 | Township |
| Saltcreek township | 8 | 2,929 | 2,743 | 1.28% | 82 | 35.87 | Township |
| Circleville township | 9 | 2,690 | 2,530 | 1.24% | 286 | 9.41 | Township |
| Pickaway township | 10 | 2,161 | 2,031 | 1.27% | 44 | 48.73 | Township |
| Deercreek township | 11 | 1,697 | 1,596 | 1.19% | 47 | 36.09 | Township |
| Williamsport | 12 | 1,036 | 975 | 1.17% | 584 | 1.77 | Village |
| Muhlenberg township | 13 | 882 | 834 | 1.03% | 39 | 22.75 | Township |
| New Holland | 14 | 846 | 806 | 0.95% | 432 | 1.96 | Village |
| Derby | 15 | 568 | 543 | 1.97% | 427 | 1.33 | CDP |
| Tarlton | 16 | 270 | 254 | 1.12% | 703 | 0.38 | Village |
| Orient | 17 | 260 | 130 | 7% | 1,699 | 0.15 | CDP |
Circleville is the largest city in Pickaway County, with a population of 14,786.
Orient is the smallest city in Pickaway County.
There are 17 cities in Pickaway County, Ohio.