45 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Tahlequah | 1 | 17,533 | 16,436 | 1.24% | 1,373 | 13 | City |
| Tahlequah | 2 | 17,533 | 16,463 | 1.24% | 1,373 | 13 | City |
| Park Hill | 3 | 3,506 | 3,704 | -0.76% | 141 | 25 | CDP |
| Norwood | 4 | 1,752 | 1,760 | 7.09% | 54 | 32 | CDP |
| Briggs | 5 | 1,393 | 998 | 5.53% | 165 | 8 | CDP |
| Moodys | 6 | 1,374 | 1,014 | 7.18% | 79 | 17 | CDP |
| Cookson | 7 | 1,369 | 988 | 7.12% | 106 | 13 | CDP |
| Woodall | 8 | 1,277 | 1,004 | 2.49% | 115 | 11 | CDP |
| Keys | 9 | 1,188 | 854 | 3.66% | 122 | 10 | CDP |
| Grandview | 10 | 1,166 | 1,237 | 4.57% | 165 | 7 | CDP |
| Peggs | 11 | 890 | 1,215 | 0.56% | 58 | 15 | CDP |
| Lost City | 12 | 769 | 799 | 0% | 33 | 24 | CDP |
| Pettit | 13 | 685 | 738 | -2.56% | 61 | 11 | CDP |
| Welling | 14 | 685 | 709 | -0.72% | 27 | 25 | CDP |
| Zeb | 15 | 567 | 577 | 0.89% | 65 | 9 | CDP |
| Shady Grove | 16 | 512 | 580 | -0.58% | 41 | 13 | CDP |
| Hulbert | 17 | 497 | 475 | 0.81% | 444 | 1 | Town |
| Hulbert | 18 | 497 | 474 | 0.81% | 444 | 1 | Town |
| Lowrey | 19 | 435 | 410 | 7.14% | 28 | 16 | CDP |
| Barber | 20 | 416 | 356 | 7.22% | 64 | 6 | CDP |
| Evening Shade | 21 | 398 | 328 | 0.76% | 30 | 13 | CDP |
| Mallard Bay | 22 | 351 | 246 | 7.01% | 166 | 2 | CDP |
| Gideon | 23 | 338 | 352 | 7.3% | 54 | 6 | CDP |
| Eldon | 24 | 317 | 151 | -0.94% | 35 | 9 | CDP |
| Snake Creek | 25 | 305 | 320 | 1.33% | 37 | 8 | CDP |
| Leach | 26 | 278 | 275 | 0.72% | 48 | 6 | CDP |
| Steely Hollow | 27 | 271 | 240 | 1.5% | 57 | 5 | CDP |
| Cedar Crest | 28 | 243 | 139 | -2.02% | 33 | 7 | CDP |
| Rocky Ford | 29 | 239 | 214 | 7.17% | 35 | 7 | CDP |
| Tenkiller | 30 | 233 | 388 | -10.38% | 15 | 16 | CDP |
| Sparrowhawk | 31 | 220 | 158 | 7.32% | 41 | 5 | CDP |
| Little Rock | 32 | 215 | 200 | 6.97% | 31 | 7 | CDP |
| Dry Creek | 33 | 212 | 153 | -0.47% | 24 | 9 | CDP |
| Teresita | 34 | 189 | 177 | 1.07% | 19 | 10 | CDP |
| Johnson Prairie | 35 | 169 | 132 | 6.96% | 35 | 5 | CDP |
| Ballou | 36 | 152 | 269 | -1.3% | 41 | 4 | CDP |
| Sams Corner | 37 | 147 | 194 | 0.68% | 153 | 1 | CDP |
| Box | 38 | 118 | 185 | -5.6% | 36 | 3 | CDP |
| Murphy | 39 | 118 | 117 | -4.84% | 29 | 4 | CDP |
| Caney Ridge | 40 | 89 | 43 | 7.23% | 316 | 0 | CDP |
| Blackgum | 41 | 68 | 83 | 7.94% | 312 | 0 | CDP |
| Pinhook Corner | 42 | 46 | 142 | -14.81% | 5 | 10 | CDP |
| Etta | 43 | 45 | 175 | 7.14% | 12 | 4 | CDP |
| Iron Post | 44 | 45 | 142 | 7.14% | 17 | 3 | CDP |
| Dwight Mission | 45 | 44 | 96 | 7.32% | 9 | 5 | CDP |
Tahlequah is the largest city in Cherokee County, with a population of 17,533.
Dwight Mission is the smallest city in Cherokee County, with a population of 44.
There are 45 cities in Cherokee County, Oklahoma.