13 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Weatherford | 1 | 12,043 | 12,086 | -0.03% | 1,573 | 8 | City |
| Weatherford | 2 | 12,043 | 12,062 | -0.03% | 1,573 | 8 | City |
| Clinton | 3 | 8,319 | 8,526 | -0.43% | 836 | 10 | City |
| Clinton | 4 | 8,319 | 8,497 | -0.43% | 836 | 10 | City |
| Thomas | 5 | 1,135 | 1,152 | -0.26% | 988 | 1 | City |
| Thomas | 6 | 1,135 | 1,149 | -0.26% | 988 | 1 | City |
| Arapaho | 7 | 661 | 666 | -0.15% | 946 | 1 | Town |
| Arapaho | 8 | 661 | 664 | -0.15% | 946 | 1 | Town |
| Custer City | 9 | 369 | 370 | 0% | 608 | 1 | Town |
| Custer City | 10 | 369 | 369 | 0% | 608 | 1 | Town |
| Butler | 11 | 206 | 209 | -0.48% | 484 | 0 | Town |
| Butler | 12 | 206 | 208 | -0.48% | 484 | 0 | Town |
| Butler | 13 | 182 | 268 | 2.25% | 65 | 3 | CDP |
Weatherford is the largest city in Custer County, with a population of 12,043.
Butler is the smallest city in Custer County, with a population of 182.
There are 13 cities in Custer County, Oklahoma.