22 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lake | 1 | 4,911 | 4,869 | 0.08% | 177 | 28 | Township |
| Honesdale | 2 | 4,434 | 4,466 | -0.16% | 1,142 | 4 | Borough |
| Salem | 3 | 4,162 | 4,120 | 0.07% | 136 | 31 | Township |
| Damascus | 4 | 3,700 | 3,673 | -0.13% | 47 | 79 | Township |
| Canaan | 5 | 3,522 | 3,610 | -0.2% | 193 | 18 | Township |
| Texas | 6 | 2,271 | 2,289 | -0.35% | 162 | 14 | Township |
| Cherry Ridge | 7 | 1,891 | 1,909 | -0.32% | 88 | 21 | Township |
| Lehigh | 8 | 1,865 | 1,875 | -0.32% | 155 | 12 | Township |
| South Canaan | 9 | 1,847 | 1,797 | 0.22% | 67 | 27 | Township |
| Sterling | 10 | 1,514 | 1,480 | 0.53% | 56 | 27 | Township |
| Dyberry | 11 | 1,429 | 1,401 | 0.56% | 64 | 22 | Township |
| Dreher | 12 | 1,376 | 1,347 | 0.22% | 93 | 15 | Township |
| Waymart | 13 | 1,283 | 1,296 | -0.23% | 477 | 3 | Borough |
| Preston | 14 | 1,011 | 994 | 0% | 20 | 49 | Township |
| Oregon | 15 | 837 | 839 | -0.36% | 47 | 18 | Township |
| White Mills | 16 | 768 | 864 | 1.05% | 518 | 1 | CDP |
| Gouldsboro | 17 | 678 | 782 | -2.02% | 264 | 3 | CDP |
| Hamlin | 18 | 660 | 683 | -0.3% | 10 | 65 | Township |
| Scott | 19 | 501 | 484 | 0.8% | 12 | 44 | Township |
| Bethany | 20 | 238 | 241 | -0.42% | 478 | 0 | Borough |
| Prompton | 21 | 236 | 236 | 0% | 154 | 2 | Borough |
| Starrucca | 22 | 172 | 170 | 0% | 19 | 9 | Borough |
Lake is the largest city in Wayne County, with a population of 4,911.
Starrucca is the smallest city in Wayne County, with a population of 172.
There are 22 cities in Wayne County, Pennsylvania.