14 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Charleston | 1 | 158,367 | 150,872 | 0.96% | 1,376 | 115.05 | City |
| North Charleston | 2 | 125,414 | 115,551 | 1.6% | 1,615 | 77.63 | City |
| Goose Creek | 3 | 51,248 | 46,250 | 1.99% | 1,207 | 42.44 | City |
| Hanahan | 4 | 22,578 | 20,622 | 1.76% | 2,136 | 10.57 | City |
| Moncks Corner | 5 | 18,743 | 13,438 | 6% | 1,638 | 11.44 | Town |
| Ladson | 6 | 15,675 | 15,252 | 0.81% | 2,229 | 7.03 | CDP |
| Sangaree | 7 | 8,795 | 9,249 | 0.43% | 4,330 | 2.03 | CDP |
| Pimlico | 8 | 2,790 | 1,450 | 7.14% | 4,067 | 0.69 | CDP |
| St. Stephen | 9 | 1,573 | 1,573 | 0% | 607 | 2.59 | Town |
| Bonneau Beach | 10 | 1,393 | 1,294 | -2.45% | 594 | 2.35 | CDP |
| Pinopolis | 11 | 929 | 1,130 | -0.11% | 649 | 1.43 | CDP |
| Bonneau | 12 | 438 | 428 | 0.46% | 145 | 3.02 | Town |
| Russellville | 13 | 228 | 173 | -6.94% | 61 | 3.74 | CDP |
| Jamestown | 14 | 71 | 71 | 0% | 117 | 0.61 | Town |
Charleston is the largest city in Berkeley County, with a population of 158,367.
Jamestown is the smallest city in Berkeley County.
There are 14 cities in Berkeley County, South Carolina.