6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Summerville | 1 | 52,406 | 51,101 | 0.5% | 2,324 | 22.55 | Town |
| St. George | 2 | 1,831 | 1,838 | -0.06% | 643 | 2.85 | Town |
| Ridgeville | 3 | 1,498 | 1,825 | -4.16% | 834 | 1.80 | Town |
| Harleyville | 4 | 749 | 671 | 2.18% | 705 | 1.06 | Town |
| Grover | 5 | 524 | 431 | 7.16% | 203 | 2.59 | CDP |
| Reevesville | 6 | 190 | 202 | -1.04% | 118 | 1.61 | Town |
Summerville is the largest city in Dorchester County, with a population of 52,406.
Reevesville is the smallest city in Dorchester County.
There are 6 cities in Dorchester County, South Carolina.