6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Greenville | 1 | 75,106 | 71,428 | 0.99% | 2,433 | 31 | City |
| Greer | 2 | 48,937 | 35,829 | 5.66% | 2,000 | 24 | City |
| Mauldin | 3 | 30,986 | 24,786 | 4.17% | 2,501 | 12 | City |
| Simpsonville | 4 | 29,196 | 23,605 | 3.98% | 3,006 | 10 | City |
| Fountain Inn | 5 | 14,604 | 10,512 | 5.93% | 1,698 | 9 | City |
| Travelers Rest | 6 | 9,245 | 7,819 | 3.18% | 1,481 | 6 | City |
Greenville is the largest city in Greenville County, with a population of 75,106.
Travelers Rest is the smallest city in Greenville County, with a population of 9,245.
There are 6 cities in Greenville County, South Carolina.