21 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Myrtle Beach | 1 | 42,179 | 35,973 | 3.03% | 1,802 | 23.41 | City |
| Carolina Forest | 2 | 31,029 | 23,426 | 7.14% | 1,845 | 16.82 | CDP |
| Conway | 3 | 29,891 | 25,125 | 3.29% | 1,211 | 24.69 | City |
| Socastee | 4 | 25,592 | 25,846 | 1.49% | 1,915 | 13.37 | CDP |
| North Myrtle Beach | 5 | 21,231 | 18,910 | 2.23% | 965 | 21.99 | City |
| Red Hill | 6 | 16,176 | 16,290 | 1.23% | 1,472 | 10.99 | CDP |
| Garden City | 7 | 11,304 | 11,193 | 1.25% | 2,115 | 5.34 | CDP |
| Murrells Inlet | 8 | 10,984 | 9,292 | 2.13% | 1,502 | 7.32 | CDP |
| Little River | 9 | 10,029 | 9,692 | 0.71% | 957 | 10.48 | CDP |
| Forestbrook | 10 | 8,114 | 7,613 | 2.96% | 2,211 | 3.67 | CDP |
| Surfside Beach | 11 | 4,429 | 4,158 | 1.23% | 2,274 | 1.95 | Town |
| Loris | 12 | 2,938 | 2,465 | 3.34% | 645 | 4.55 | City |
| Homewood | 13 | 1,612 | 1,642 | 7.11% | 794 | 2.03 | CDP |
| Aynor | 14 | 1,097 | 982 | 2.14% | 609 | 1.80 | Town |
| Bucksport | 15 | 711 | 607 | -1.52% | 169 | 4.20 | CDP |
| Finklea | 16 | 649 | 426 | 7.1% | 241 | 2.69 | CDP |
| Briarcliffe Acres | 17 | 585 | 484 | 3.54% | 920 | 0.64 | Town |
| Atlantic Beach | 18 | 458 | 200 | 12.81% | 2,827 | 0.16 | Town |
| Nichols | 19 | 218 | 230 | -0.91% | 163 | 1.34 | Town |
| Green Sea | 20 | 79 | 70 | 6.76% | 45 | 1.76 | CDP |
| Live Oak | 21 | 11 | 66 | 10% | 13 | 0.84 | CDP |
Myrtle Beach is the largest city in Horry County, with a population of 42,179.
Live Oak is the smallest city in Horry County, with a population of 11.
There are 21 cities in Horry County, South Carolina.