5 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Bennettsville | 1 | 7,496 | 7,989 | -1.3% | 1,214 | 6 | City |
| McColl | 2 | 1,953 | 2,067 | -1.16% | 1,860 | 1 | Town |
| Clio | 3 | 566 | 603 | -1.39% | 661 | 1 | Town |
| Blenheim | 4 | 105 | 113 | -1.87% | 161 | 1 | Town |
| Tatum | 5 | 69 | 74 | -1.43% | 76 | 1 | Town |
Bennettsville is the largest city in Marlboro County, with a population of 7,496.
Tatum is the smallest city in Marlboro County, with a population of 69.
There are 5 cities in Marlboro County, South Carolina.