St. James is a city located in Missouri. With a 2020 population of 3,983, it is the 165th largest city in Missouri and the 5412th largest city in the United States. St. James is currently declining at a rate of -1.04% annually and its population has decreased by -5.53% since the most recent census, which recorded a population of 4,216 in 2010. St. James reached it's highest population of 4,224 in 2010. Spanning over 4 miles, St. James has a population density of 932 people per square mile.
The average household income in St. James is $51,408 with a poverty rate of 18.34%. The median rental costs in recent years comes to $667 per month, and the median house value is $89,800. The median age in St. James is 37.9 years, 35.6 years for males, and 44.7 years for females. For every 100 females there are 113.2 males.