6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lexington | 1 | 8,011 | 7,953 | 0.15% | 681 | 11.76 | City |
| Chesterfield | 2 | 925 | 706 | 3.35% | 120 | 7.68 | CDP |
| Darden | 3 | 420 | 372 | 0.24% | 50 | 8.39 | CDP |
| Sardis | 4 | 418 | 412 | 0.24% | 167 | 2.50 | Town |
| Wildersville | 5 | 206 | 279 | 7.29% | 122 | 1.68 | CDP |
| Huron | 6 | 165 | 107 | 7.14% | 166 | 0.99 | CDP |
Lexington is the largest city in Henderson County, with a population of 8,011.
Huron is the smallest city in Henderson County.
There are 6 cities in Henderson County, Tennessee.