10 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Henderson | 1 | 13,539 | 13,275 | 0.4% | 1,133 | 12 | City |
| Henderson | 2 | 13,539 | 13,269 | 0.4% | 1,133 | 12 | City |
| Overton | 3 | 2,312 | 2,276 | 0.3% | 345 | 7 | City |
| Overton | 4 | 2,312 | 2,277 | 0.3% | 345 | 7 | City |
| Tatum | 5 | 1,413 | 1,345 | 0.93% | 374 | 4 | City |
| Tatum | 6 | 1,413 | 1,348 | 0.93% | 374 | 4 | City |
| New London | 7 | 994 | 963 | 0.61% | 115 | 9 | City |
| New London | 8 | 994 | 963 | 0.61% | 115 | 9 | City |
| Mount Enterprise | 9 | 513 | 505 | 0.2% | 345 | 1 | City |
| Mount Enterprise | 10 | 513 | 505 | 0.2% | 345 | 1 | City |
Henderson is the largest city in Rusk County, with a population of 13,539.
Mount Enterprise is the smallest city in Rusk County, with a population of 513.
There are 10 cities in Rusk County, Texas.