13 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Casper | 1 | 58,327 | 59,309 | -0.33% | 2,180 | 27 | City |
| Mills | 2 | 4,711 | 4,226 | 2.1% | 925 | 5 | Town |
| Bar Nunn | 3 | 2,997 | 3,006 | -0.07% | 1,428 | 2 | Town |
| Evansville | 4 | 2,774 | 2,783 | -0.07% | 706 | 4 | Town |
| Hartrandt | 5 | 956 | 1,016 | 1.92% | 612 | 2 | CDP |
| Red Butte | 6 | 835 | 987 | 3.09% | 1,906 | 0 | CDP |
| Vista West | 7 | 784 | 724 | -1.38% | 168 | 5 | CDP |
| Casper Mountain | 8 | 738 | 965 | 3.07% | 21 | 36 | CDP |
| Midwest | 9 | 284 | 288 | -0.35% | 586 | 0 | Town |
| Homa Hills | 10 | 183 | 196 | -3.17% | 20 | 9 | CDP |
| Edgerton | 11 | 154 | 154 | 0% | 517 | 0 | Town |
| Alcova | 12 | 105 | 30 | 7.14% | 87 | 1 | CDP |
| Bessemer Bend | 13 | 98 | 122 | -5.77% | 39 | 3 | CDP |
Casper is the largest city in Natrona County, with a population of 58,327.
Bessemer Bend is the smallest city in Natrona County, with a population of 98.
There are 13 cities in Natrona County, Wyoming.