
Luzerne County
- State:
- Pennsylvania
- County Seat:
- Wilkes-Barre
Luzerne County's estimated 2025 population is 329,172 with a growth rate of 0.27% in the past year according to the most recent United States census data. Luzerne County is the 12th largest county in Pennsylvania. The 2010 population was 321,017 and has seen a growth of 2.54% since that time.