Antofagasta's 2021 population is now estimated at 445,302. In 1950, the population of Antofagasta was 57,906. Antofagasta has grown by 6,431 since 2015, which represents a 1.47% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Antofagasta, which typically includes Antofagasta's population in addition to adjacent suburban areas.