Larkana's 2021 population is now estimated at 548,916. In 1950, the population of Larkana was 33,054. Larkana has grown by 14,628 since 2015, which represents a 2.74% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Larkana, which typically includes Larkana's population in addition to adjacent suburban areas.