Manizales's 2021 population is now estimated at 450,051. In 1950, the population of Manizales was 87,641. Manizales has grown by 2,016 since 2015, which represents a 0.45% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Manizales, which typically includes Manizales's population in addition to adjacent suburban areas.