Matamoros's 2021 population is now estimated at 570,752. In 1950, the population of Matamoros was 45,957. Matamoros has grown by 7,997 since 2015, which represents a 1.42% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Matamoros, which typically includes Matamoros's population in addition to adjacent suburban areas.