Phoenix-Mesa's 2021 population is now estimated at 4,583,752. In 1950, the population of Phoenix-Mesa was 221,150. Phoenix-Mesa has grown by 72,332 since 2015, which represents a 1.60% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Phoenix-Mesa, which typically includes Phoenix-Mesa's population in addition to adjacent suburban areas.