9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Bay City | 1 | 17,241 | 18,041 | -0.92% | 1,860 | 9.27 | City |
| Palacios | 2 | 4,356 | 4,400 | -0.21% | 798 | 5.46 | City |
| Sargent | 3 | 1,550 | 1,204 | 7.12% | 208 | 7.45 | CDP |
| Markham | 4 | 1,257 | 1,029 | 0.96% | 559 | 2.25 | CDP |
| Van Vleck | 5 | 850 | 1,293 | -7.21% | 117 | 7.29 | CDP |
| Wadsworth | 6 | 447 | 428 | 6.94% | 60 | 7.47 | CDP |
| Matagorda | 7 | 353 | 519 | -2.75% | 191 | 1.84 | CDP |
| Blessing | 8 | 190 | 482 | -20.5% | 94 | 2.03 | CDP |
| Midfield | 9 | 16 | 231 | 6.67% | 35 | 0.46 | CDP |
Bay City is the largest city in Matagorda County, with a population of 17,241.
Midfield is the smallest city in Matagorda County.
There are 9 cities in Matagorda County, Texas.