5 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Aliceville | 1 | 1,974 | 2,165 | -1.6% | 432 | 5 | City |
| Gordo | 2 | 1,524 | 1,628 | -1.1% | 468 | 3 | Town |
| Reform | 3 | 1,397 | 1,517 | -1.41% | 174 | 8 | Town |
| Carrollton | 4 | 944 | 1,016 | -1.26% | 459 | 2 | Town |
| Ethelsville | 5 | 46 | 51 | -2.13% | 81 | 1 | Town |
Aliceville is the largest city in Pickens County, with a population of 1,974.
Ethelsville is the smallest city in Pickens County, with a population of 46.
There are 5 cities in Pickens County, Alabama.