| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Aliceville | 1 | 1,992 | 2,169 | -1.58% | 436 | 5 | City |
| Gordo | 2 | 1,537 | 1,630 | -1.03% | 472 | 3 | Town |
| Reform | 3 | 1,411 | 1,513 | -1.47% | 176 | 8 | Town |
| Carrollton | 4 | 954 | 1,016 | -1.24% | 464 | 2 | Town |
| Ethelsville | 5 | 46 | 51 | -2.13% | 81 | 1 | Town |
Aliceville is the largest city in Pickens County, with a population of 1,992.
Ethelsville is the smallest city in Pickens County, with a population of 46.
There are 5 cities in Pickens County, Alabama.