| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Auburn | 1 | 86,786 | 77,119 | 1.97% | 1,354 | 64 | City |
| Phenix City | 2 | 38,282 | 38,821 | -0.16% | 1,364 | 28 | City |
| Opelika | 3 | 36,750 | 31,087 | 2.75% | 593 | 62 | City |
| Smiths Station | 4 | 5,634 | 5,441 | 0.68% | 689 | 8 | City |
| Loachapoka | 5 | 168 | 165 | 0.6% | 148 | 1 | Town |
| Cusseta | 6 | 156 | 152 | 0.65% | 59 | 3 | Town |
| Waverly | 7 | 150 | 150 | 0% | 54 | 3 | Town |
Auburn is the largest city in Lee County, with a population of 86,786.
Waverly is the smallest city in Lee County, with a population of 150.
There are 7 cities in Lee County, Alabama.