City | Rank | 2024 Population | 2020 Population | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Charleston | 1 | 156,868 | 150,872 | 0.97% | 1,363 | 115.1 | City |
| Columbia | 2 | 144,489 | 136,195 | 1.46% | 1,045 | 138.3 | City |
| North Charleston | 3 | 123,441 | 115,551 | 1.62% | 1,590 | 77.6 | City |
| Mount Pleasant | 4 | 96,567 | 91,225 | 1.4% | 1,945 | 49.6 | Town |
| Rock Hill | 5 | 75,971 | 74,701 | 0.42% | 1,714 | 44.3 | City |
| Greenville | 6 | 73,394 | 71,114 | 0.78% | 2,440 | 30.1 | City |
| Summerville | 7 | 52,145 | 51,101 | 0.5% | 2,313 | 22.5 | Town |
| Goose Creek | 8 | 50,248 | 46,250 | 2.03% | 1,184 | 42.4 | City |
| Greer | 9 | 47,250 | 35,797 | 6.45% | 2,013 | 23.5 | City |
| Sumter | 10 | 42,548 | 43,420 | -0.51% | 1,288 | 33.0 | City |
| Myrtle Beach | 11 | 40,938 | 35,973 | 3.13% | 1,749 | 23.4 | City |
| Florence | 12 | 40,779 | 40,097 | 0.42% | 1,665 | 24.5 | City |
| Spartanburg | 13 | 39,184 | 38,608 | 0.37% | 1,935 | 20.3 | City |
| Hilton Head Island | 14 | 38,267 | 37,587 | 0.45% | 925 | 41.4 | Town |
| Bluffton | 15 | 37,544 | 28,338 | 6.53% | 720 | 52.1 | Town |
| Fort Mill | 16 | 36,438 | 25,188 | 8.36% | 1,849 | 19.7 | Town |
| Aiken | 17 | 33,216 | 32,139 | 0.82% | 1,534 | 21.6 | City |
| Anderson | 18 | 30,148 | 29,476 | 0.56% | 1,883 | 16.0 | City |
| Mauldin | 19 | 29,088 | 24,776 | 3.85% | 2,348 | 12.4 | City |
| Carolina Forest | 20 | 28,960 | 23,426 | 7.69% | 1,722 | 16.8 | CDP |
| Conway | 21 | 28,938 | 25,125 | 3.4% | 1,172 | 24.7 | City |
| Simpsonville | 22 | 28,807 | 23,601 | 4.73% | 3,043 | 9.5 | City |
| Easley | 23 | 27,503 | 23,035 | 4.23% | 2,091 | 13.2 | City |
| North Augusta | 24 | 26,359 | 24,487 | 1.81% | 1,238 | 21.3 | City |
| Lexington | 25 | 25,343 | 23,653 | 1.69% | 2,117 | 12.0 | Town |
| Socastee | 26 | 25,216 | 25,846 | 1.51% | 1,887 | 13.4 | CDP |
| Taylors | 27 | 23,236 | 23,107 | 0.5% | 2,200 | 10.6 | CDP |
| Greenwood | 28 | 22,477 | 22,560 | -0.09% | 1,348 | 16.7 | City |
| Hanahan | 29 | 22,187 | 20,622 | 1.79% | 2,099 | 10.6 | City |
| St. Andrews | 30 | 22,145 | 21,355 | 0.54% | 3,605 | 6.1 | CDP |
| Wade Hampton | 31 | 21,097 | 20,192 | 0.16% | 2,375 | 8.9 | CDP |
| North Myrtle Beach | 32 | 20,767 | 18,910 | 2.28% | 944 | 22.0 | City |
| Five Forks | 33 | 19,334 | 19,399 | 1.96% | 2,554 | 7.6 | CDP |
| West Columbia | 34 | 18,581 | 17,519 | 1.45% | 1,982 | 9.4 | City |
| Clemson | 35 | 17,866 | 17,753 | 0.16% | 2,258 | 7.9 | City |
| Moncks Corner | 36 | 17,682 | 13,438 | 6.38% | 1,545 | 11.4 | Town |
| Port Royal | 37 | 16,881 | 14,503 | 3.65% | 995 | 17.0 | Town |
| Dentsville | 38 | 16,788 | 15,537 | 1.17% | 2,509 | 6.7 | CDP |
| Berea | 39 | 16,499 | 15,104 | 0.97% | 2,143 | 7.7 | CDP |
| Red Hill | 40 | 15,979 | 16,290 | 1.25% | 1,454 | 11.0 | CDP |
| Seven Oaks | 41 | 15,940 | 16,743 | 0.36% | 2,083 | 7.7 | CDP |
| Ladson | 42 | 15,549 | 15,252 | 0.81% | 2,211 | 7.0 | CDP |
| Lake Wylie | 43 | 15,306 | 14,091 | 3.11% | 1,940 | 7.9 | CDP |
| Tega Cay | 44 | 14,434 | 12,924 | 2.68% | 3,140 | 4.6 | City |
| Gantt | 45 | 14,284 | 14,556 | 0.03% | 1,460 | 9.8 | CDP |
| Beaufort | 46 | 13,935 | 13,594 | 0.61% | 570 | 24.4 | City |
| Fountain Inn | 47 | 13,864 | 10,514 | 6.42% | 1,612 | 8.6 | City |
| Cayce | 48 | 13,627 | 13,758 | -0.24% | 807 | 16.9 | City |
| Orangeburg | 49 | 13,316 | 13,170 | 0.27% | 1,478 | 9.0 | City |
| Hardeeville | 50 | 13,288 | 7,723 | 11.69% | 234 | 56.7 | City |
| Parker | 51 | 12,638 | 12,175 | 0.69% | 1,848 | 6.8 | CDP |
| Powdersville | 52 | 12,458 | 9,436 | 7.69% | 906 | 13.8 | CDP |
| Gaffney | 53 | 12,398 | 12,742 | -0.69% | 1,382 | 9.0 | City |
| Irmo | 54 | 12,174 | 11,609 | 1.17% | 1,732 | 7.0 | Town |
| James Island | 55 | 11,984 | 11,658 | 0.68% | 2,526 | 4.7 | Town |
| Boiling Springs | 56 | 11,686 | 9,953 | 2.16% | 1,709 | 6.8 | CDP |
| Oak Grove | 57 | 11,567 | 12,040 | 0.79% | 1,526 | 7.6 | CDP |
| Garden City | 58 | 11,164 | 11,193 | 1.26% | 2,089 | 5.3 | CDP |
| Newberry | 59 | 10,925 | 10,687 | 0.54% | 1,215 | 9.0 | City |
| Murrells Inlet | 60 | 10,755 | 9,292 | 2.18% | 1,470 | 7.3 | CDP |
| Red Bank | 61 | 10,698 | 9,971 | 0.73% | 853 | 12.5 | CDP |
| Litchfield Beach | 62 | 10,393 | 8,702 | 7.7% | 926 | 11.2 | CDP |
| Forest Acres | 63 | 10,307 | 10,581 | -0.66% | 2,229 | 4.6 | City |
| Little River | 64 | 9,958 | 9,692 | 0.73% | 950 | 10.5 | CDP |
| Lugoff | 65 | 9,754 | 9,146 | 1.72% | 428 | 22.8 | CDP |
| Woodfield | 66 | 9,493 | 9,361 | 0.14% | 3,486 | 2.7 | CDP |
| York | 67 | 9,353 | 8,555 | 2.17% | 1,103 | 8.5 | City |
| Lancaster | 68 | 9,296 | 8,523 | 2.12% | 1,307 | 7.1 | City |
| Laurens | 69 | 9,263 | 9,363 | -0.27% | 907 | 10.2 | City |
| Seneca | 70 | 9,105 | 8,856 | 0.69% | 1,105 | 8.2 | City |
| Travelers Rest | 71 | 9,060 | 7,818 | 3.54% | 1,452 | 6.2 | City |
| Georgetown | 72 | 8,820 | 8,396 | 1.22% | 1,261 | 7.0 | City |
| Sangaree | 73 | 8,757 | 9,249 | 0.45% | 4,312 | 2.0 | CDP |
| Camden | 74 | 8,639 | 7,805 | 2.47% | 778 | 11.1 | City |
| White Knoll | 75 | 8,382 | 7,476 | 7.68% | 1,370 | 6.1 | CDP |
| Sans Souci | 76 | 8,071 | 8,844 | 0.19% | 2,438 | 3.3 | CDP |
| Forestbrook | 77 | 7,881 | 7,613 | 3.05% | 2,147 | 3.7 | CDP |
| Union | 78 | 7,793 | 8,144 | -1.12% | 975 | 8.0 | City |
| Clinton | 79 | 7,742 | 7,630 | 0.36% | 741 | 10.4 | City |
| Burton | 80 | 7,708 | 8,779 | 0.69% | 923 | 8.4 | CDP |
| Homeland Park | 81 | 7,644 | 6,570 | 1.29% | 1,623 | 4.7 | CDP |
| Clover | 82 | 7,608 | 6,740 | 2.94% | 1,609 | 4.7 | Town |
| Hartsville | 83 | 7,388 | 7,430 | -0.15% | 1,233 | 6.0 | City |
| Centerville | 84 | 7,322 | 6,816 | 0.71% | 1,240 | 5.9 | CDP |
| Clemson University | 85 | 7,253 | 5,329 | 7.69% | 3,426 | 2.1 | CDP |
| Valley Falls | 86 | 7,238 | 7,269 | 0.93% | 1,395 | 5.2 | CDP |
| Welcome | 87 | 7,234 | 7,743 | 0.57% | 1,568 | 4.6 | CDP |
| Lake Murray Richland | 88 | 7,152 | 6,672 | 1.69% | 1,289 | 5.5 | CDP |
| Lyman | 89 | 6,876 | 6,206 | 2.49% | 1,038 | 6.6 | Town |
| Blythewood | 90 | 6,734 | 4,864 | 7.45% | 634 | 10.6 | Town |
| Bennettsville | 91 | 6,426 | 6,881 | -1.74% | 1,040 | 6.2 | City |
| Dillon | 92 | 6,239 | 6,507 | -1.06% | 1,169 | 5.3 | City |
| Marion | 93 | 6,121 | 6,416 | -1.2% | 1,367 | 4.5 | City |
| Darlington | 94 | 6,012 | 6,192 | -0.74% | 1,276 | 4.7 | City |
| Lake City | 95 | 5,936 | 6,035 | -0.42% | 1,089 | 5.5 | City |
| Belvedere | 96 | 5,785 | 5,557 | -0.02% | 1,690 | 3.4 | CDP |
| Piedmont | 97 | 5,578 | 6,122 | 0.61% | 649 | 8.6 | CDP |
| Hollywood | 98 | 5,494 | 5,297 | 0.9% | 234 | 23.5 | Town |
| Walterboro | 99 | 5,464 | 5,506 | -0.2% | 798 | 6.8 | City |
| Laurel Bay | 100 | 5,450 | 6,388 | -0.58% | 1,309 | 4.2 | CDP |
| Central | 101 | 5,340 | 5,268 | 0.34% | 1,643 | 3.3 | Town |
| Batesburg-Leesville | 102 | 5,309 | 5,261 | 0.23% | 648 | 8.2 | Town |
| Chester | 103 | 5,211 | 5,273 | -0.31% | 1,576 | 3.3 | City |
| Baxter Village | 104 | 5,156 | 4,694 | 7.71% | 3,626 | 1.4 | CDP |
| Cheraw | 105 | 4,983 | 5,029 | -0.24% | 837 | 6.0 | Town |
| Abbeville | 106 | 4,863 | 4,862 | 0% | 782 | 6.2 | City |
| Woodruff | 107 | 4,683 | 4,227 | 2.5% | 923 | 5.1 | City |
| Belton | 108 | 4,567 | 4,343 | 1.24% | 1,196 | 3.8 | City |
| India Hook | 109 | 4,561 | 3,762 | 1.97% | 1,730 | 2.6 | CDP |
| Barnwell | 110 | 4,554 | 4,646 | -0.5% | 581 | 7.8 | City |
| Duncan | 111 | 4,553 | 4,065 | 2.75% | 726 | 6.3 | Town |
| Wyboo | 112 | 4,417 | 4,027 | 7.68% | 295 | 15.0 | CDP |
| Isle Palms | 113 | 4,377 | 4,348 | 0.16% | 987 | 4.4 | City |
| Surfside Beach | 114 | 4,375 | 4,158 | 1.25% | 2,246 | 1.9 | Town |
| Whitney | 115 | 4,356 | 3,999 | 7.69% | 1,428 | 3.1 | CDP |
| Saxon | 116 | 4,296 | 3,727 | 1.49% | 1,804 | 2.4 | CDP |
| Williamston | 117 | 4,274 | 4,054 | 1.3% | 1,159 | 3.7 | Town |
| Newport | 118 | 4,241 | 4,432 | 0.17% | 527 | 8.0 | CDP |
| Walhalla | 119 | 4,238 | 4,081 | 0.93% | 1,091 | 3.9 | City |
| East Camden | 120 | 4,181 | 3,909 | 7.67% | 1,168 | 3.6 | CDP |
| Roebuck | 121 | 4,110 | 2,768 | 3.45% | 958 | 4.3 | CDP |
| Edgefield | 122 | 4,098 | 3,910 | 1.16% | 946 | 4.3 | Town |
| Capitol View | 123 | 4,073 | 3,604 | 7.69% | 2,520 | 1.6 | CDP |
| Northlake | 124 | 4,030 | 3,684 | 0.52% | 974 | 4.1 | CDP |
| Brookdale | 125 | 3,935 | 4,740 | -1.67% | 1,080 | 3.6 | CDP |
| Honea Path | 126 | 3,900 | 3,690 | 1.35% | 1,110 | 3.5 | Town |
| Southern Shops | 127 | 3,871 | 3,965 | 0.21% | 1,086 | 3.6 | CDP |
| Mullins | 128 | 3,844 | 4,008 | -1.05% | 1,272 | 3.0 | City |
| Hilltop | 129 | 3,795 | 3,483 | 7.69% | 2,079 | 1.8 | CDP |
| Manning | 130 | 3,782 | 3,862 | -0.53% | 1,289 | 2.9 | City |
| Ridgeland | 131 | 3,751 | 3,743 | 0.05% | 78 | 48.3 | Town |
| Wellford | 132 | 3,718 | 3,354 | 2.51% | 812 | 4.6 | City |
| Pendleton | 133 | 3,709 | 3,499 | 1.42% | 756 | 4.9 | Town |
| Keowee Key | 134 | 3,569 | 2,757 | 7.7% | 1,029 | 3.5 | CDP |
| Arthurtown | 135 | 3,508 | 2,793 | 7.67% | 1,885 | 1.9 | CDP |
| Dalzell | 136 | 3,477 | 3,086 | 0.87% | 595 | 5.8 | CDP |
| Golden Grove | 137 | 3,418 | 3,449 | 2.03% | 592 | 5.8 | CDP |
| Pickens | 138 | 3,388 | 3,400 | -0.09% | 1,108 | 3.1 | City |
| Dunean | 139 | 3,386 | 3,099 | -0.62% | 2,159 | 1.6 | CDP |
| Inman | 140 | 3,329 | 3,007 | 2.46% | 1,898 | 1.8 | City |
| Liberty | 141 | 3,289 | 3,367 | -0.6% | 678 | 4.8 | City |
| North Hartsville | 142 | 3,263 | 1,972 | 0.03% | 720 | 4.5 | CDP |
| Clearwater | 143 | 3,242 | 4,060 | -2.41% | 773 | 4.2 | CDP |
| Burnettown | 144 | 3,233 | 3,056 | 1.38% | 587 | 5.5 | Town |
| Winnsboro | 145 | 3,230 | 3,366 | -1.04% | 884 | 3.7 | Town |
| Lakewood | 146 | 3,152 | 2,919 | 0.25% | 418 | 7.5 | CDP |
| Gloverville | 147 | 3,144 | 3,008 | 0.74% | 867 | 3.6 | CDP |
| Lesslie | 148 | 3,114 | 3,185 | 0% | 514 | 6.1 | CDP |
| Denmark | 149 | 3,077 | 3,165 | -0.71% | 788 | 3.9 | City |
| Saluda | 150 | 3,053 | 3,112 | -0.49% | 940 | 3.2 | Town |
| Arkwright | 151 | 3,020 | 2,493 | 7.66% | 1,169 | 2.6 | CDP |
| Kingstree | 152 | 3,019 | 3,231 | -1.73% | 949 | 3.2 | Town |
| Bamberg | 153 | 2,958 | 3,064 | -0.91% | 827 | 3.6 | Town |
| East Gaffney | 154 | 2,953 | 3,043 | -0.34% | 977 | 3.0 | CDP |
| Elgin | 155 | 2,928 | 2,865 | 0.79% | 603 | 4.9 | CDP |
| Cherryvale | 156 | 2,901 | 3,298 | 1.01% | 1,604 | 1.8 | CDP |
| Arcadia | 157 | 2,881 | 2,991 | 0.59% | 1,470 | 2.0 | CDP |
| Williston | 158 | 2,851 | 2,890 | -0.35% | 318 | 9.0 | Town |
| Loris | 159 | 2,843 | 2,465 | 3.42% | 624 | 4.6 | City |
| Bishopville | 160 | 2,818 | 2,994 | -1.54% | 1,206 | 2.3 | City |
| Landrum | 161 | 2,765 | 2,491 | 2.52% | 1,045 | 2.6 | City |
| Springdale | 162 | 2,713 | 2,739 | -0.26% | 1,003 | 2.7 | Town |
| Ravenel | 163 | 2,671 | 2,553 | 1.1% | 203 | 13.2 | Town |
| Pimlico | 164 | 2,604 | 1,450 | 7.69% | 3,796 | 0.7 | CDP |
| Springdale | 165 | 2,581 | 2,878 | 0.04% | 611 | 4.2 | CDP |
| Hampton | 166 | 2,578 | 2,704 | -1.23% | 571 | 4.5 | Town |
| Pacolet | 167 | 2,540 | 2,288 | 2.54% | 440 | 5.8 | Town |
| Andrews | 168 | 2,531 | 2,589 | -0.59% | 1,145 | 2.2 | Town |
| Ben Avon | 169 | 2,521 | 2,189 | 7.69% | 1,509 | 1.7 | CDP |
| Pageland | 170 | 2,514 | 2,474 | 0.4% | 518 | 4.9 | Town |
| Graniteville | 171 | 2,440 | 2,566 | -0.53% | 738 | 3.3 | CDP |
| Westminster | 172 | 2,433 | 2,353 | 0.83% | 706 | 3.4 | City |
| Allendale | 173 | 2,426 | 2,681 | -2.57% | 733 | 3.3 | Town |
| South Congaree | 174 | 2,388 | 2,374 | 0.13% | 726 | 3.3 | Town |
| New Ellenton | 175 | 2,356 | 2,216 | 1.51% | 531 | 4.4 | Town |
| Pine Ridge | 176 | 2,330 | 2,180 | 1.61% | 496 | 4.7 | Town |
| Tigerville | 177 | 2,257 | 2,023 | 3.06% | 1,698 | 1.3 | CDP |
| Cowpens | 178 | 2,244 | 2,027 | 2.47% | 978 | 2.3 | Town |
| Riverview | 179 | 2,232 | 2,479 | 5.23% | 1,788 | 1.2 | CDP |
| Slater-Marietta | 180 | 2,203 | 2,098 | 0.09% | 511 | 4.3 | CDP |
| Johnston | 181 | 2,179 | 2,001 | 2.06% | 831 | 2.6 | Town |
| Privateer | 182 | 2,165 | 2,487 | -0.6% | 265 | 8.2 | CDP |
| Wedgefield | 183 | 2,122 | 1,916 | 1.73% | 250 | 8.5 | CDP |
| Seabrook Island | 184 | 2,119 | 2,055 | 0.76% | 357 | 5.9 | Town |
| Timmonsville | 185 | 2,106 | 2,101 | 0.05% | 758 | 2.8 | Town |
| Folly Beach | 186 | 2,084 | 2,079 | 0.05% | 167 | 12.5 | City |
| Watts Mills | 187 | 2,076 | 1,970 | 1.57% | 915 | 2.3 | CDP |
| Ninety Six | 188 | 2,056 | 2,074 | -0.24% | 1,128 | 1.8 | Town |
| McCormick | 189 | 2,030 | 2,218 | -2.26% | 501 | 4.1 | Town |
| Mayo | 190 | 1,980 | 1,770 | 1.38% | 651 | 3.0 | CDP |
| Camp Croft | 191 | 1,975 | 1,991 | 7.69% | 746 | 2.6 | CDP |
| Shell Point | 192 | 1,974 | 2,991 | -1.3% | 492 | 4.0 | CDP |
| Kershaw | 193 | 1,973 | 1,700 | 3.57% | 1,062 | 1.9 | Town |
| McColl | 194 | 1,968 | 2,068 | -1.25% | 1,874 | 1.1 | Town |
| Kiawah Island | 195 | 1,962 | 2,014 | -0.66% | 176 | 11.2 | Town |
| Eureka Mill | 196 | 1,958 | 2,121 | 1.82% | 1,556 | 1.3 | CDP |
| Irwin | 197 | 1,945 | 1,308 | 1.99% | 652 | 3.0 | CDP |
| Chapin | 198 | 1,938 | 1,817 | 1.57% | 979 | 2.0 | Town |
| Sullivan's Island | 199 | 1,930 | 1,898 | 0.42% | 773 | 2.5 | Town |
| Blacksburg | 200 | 1,920 | 1,886 | 0.42% | 1,026 | 1.9 | Town |
| Great Falls | 201 | 1,920 | 1,948 | -0.36% | 453 | 4.2 | Town |
| Blackville | 202 | 1,900 | 1,926 | -0.37% | 213 | 8.9 | Town |
| Judson | 203 | 1,850 | 1,412 | -0.8% | 2,354 | 0.8 | CDP |
| St. George | 204 | 1,832 | 1,838 | -0.11% | 644 | 2.8 | Town |
| Langley | 205 | 1,831 | 2,179 | 1.55% | 1,612 | 1.1 | CDP |
| Reidville | 206 | 1,831 | 1,645 | 2.58% | 1,040 | 1.8 | Town |
| Wilkinson Heights | 207 | 1,823 | 1,863 | -2.56% | 610 | 3.0 | CDP |
| St. Matthews | 208 | 1,822 | 1,841 | -0.27% | 948 | 1.9 | Town |
| Stateburg | 209 | 1,799 | 1,912 | 1.7% | 386 | 4.7 | CDP |
| Edisto | 210 | 1,795 | 1,993 | -2.92% | 341 | 5.3 | CDP |
| Monarch Mill | 211 | 1,758 | 1,264 | -0.23% | 313 | 5.6 | CDP |
| City View | 212 | 1,754 | 1,607 | 1.68% | 4,521 | 0.4 | CDP |
| Estill | 213 | 1,751 | 1,813 | -0.91% | 542 | 3.2 | Town |
| Calhoun Falls | 214 | 1,732 | 1,724 | 0.12% | 511 | 3.4 | Town |
| Ware Shoals | 215 | 1,702 | 1,704 | -0.06% | 519 | 3.3 | Town |
| Utica | 216 | 1,682 | 1,761 | 0.84% | 1,486 | 1.1 | CDP |
| Elgin | 217 | 1,649 | 1,631 | 0.24% | 1,524 | 1.1 | Town |
| Winnsboro Mills | 218 | 1,646 | 2,099 | -1.08% | 670 | 2.5 | CDP |
| Gaston | 219 | 1,639 | 1,611 | 0.43% | 308 | 5.3 | Town |
| Jackson | 220 | 1,629 | 1,527 | 1.56% | 463 | 3.5 | Town |
| Arial | 221 | 1,618 | 2,158 | -3.92% | 355 | 4.6 | CDP |
| Fairforest | 222 | 1,615 | 1,484 | -0.31% | 772 | 2.1 | CDP |
| Varnville | 223 | 1,606 | 1,670 | -0.99% | 419 | 3.8 | Town |
| Cane Savannah | 224 | 1,604 | 1,052 | 2.23% | 442 | 3.6 | CDP |
| Beech Island | 225 | 1,588 | 1,165 | 7.73% | 323 | 4.9 | CDP |
| St. Stephen | 226 | 1,573 | 1,573 | 0% | 607 | 2.6 | Town |
| Ridgeville | 227 | 1,563 | 1,825 | -4.05% | 870 | 1.8 | Town |
| Hopkins | 228 | 1,547 | 2,068 | -5.84% | 94 | 16.5 | CDP |
| Homewood | 229 | 1,505 | 1,642 | 7.65% | 741 | 2.0 | CDP |
| Murphys Estates | 230 | 1,483 | 1,563 | 0.2% | 723 | 2.1 | CDP |
| Awendaw | 231 | 1,465 | 1,409 | 0.97% | 84 | 17.3 | Town |
| Catawba | 232 | 1,455 | 1,069 | 0.55% | 146 | 10.0 | CDP |
| Meggett | 233 | 1,443 | 1,394 | 0.84% | 80 | 18.1 | Town |
| Whitmire | 234 | 1,434 | 1,393 | 0.7% | 1,147 | 1.3 | Town |
| Olympia | 235 | 1,430 | 1,098 | 7.68% | 2,000 | 0.7 | CDP |
| Bonneau Beach | 236 | 1,428 | 1,294 | -2.46% | 609 | 2.3 | CDP |
| South Sumter | 237 | 1,423 | 2,249 | -4.69% | 609 | 2.3 | CDP |
| Pelzer | 238 | 1,422 | 1,345 | 1.35% | 1,556 | 0.9 | Town |
| Conestee | 239 | 1,414 | 1,254 | 7.69% | 1,334 | 1.1 | CDP |
| Joanna | 240 | 1,384 | 1,270 | -0.79% | 441 | 3.1 | CDP |
| Chesterfield | 241 | 1,364 | 1,352 | 0.22% | 334 | 4.1 | Town |
| Johnsonville | 242 | 1,364 | 1,379 | -0.29% | 645 | 2.1 | City |
| Fairfax | 243 | 1,349 | 1,487 | -2.53% | 407 | 3.3 | Town |
| Edmund | 244 | 1,340 | 930 | 7.63% | 196 | 6.8 | CDP |
| Gadsden | 245 | 1,330 | 983 | -1.55% | 116 | 11.5 | CDP |
| Lake Secession | 246 | 1,273 | 976 | 1.03% | 219 | 5.8 | CDP |
| Seabrook | 247 | 1,268 | 1,456 | 7.64% | 230 | 5.5 | CDP |
| Holly Hill | 248 | 1,240 | 1,286 | -0.96% | 949 | 1.3 | Town |
| Latta | 249 | 1,238 | 1,292 | -1.12% | 1,130 | 1.1 | Town |
| Dunbar | 250 | 1,236 | 1,058 | 7.76% | 1,215 | 1.0 | CDP |
| Prosperity | 251 | 1,224 | 1,175 | 0.99% | 621 | 2.0 | Town |
| Due West | 252 | 1,216 | 1,215 | 0% | 744 | 1.6 | Town |
| Lincolnville | 253 | 1,198 | 1,154 | 0.93% | 998 | 1.2 | Town |
| Iva | 254 | 1,188 | 1,130 | 1.19% | 1,160 | 1.0 | Town |
| Drayton | 255 | 1,180 | 1,097 | 7.76% | 842 | 1.4 | CDP |
| La France | 256 | 1,156 | 856 | 7.63% | 892 | 1.3 | CDP |
| Buffalo | 257 | 1,141 | 1,020 | -0.78% | 284 | 4.0 | CDP |
| Cateechee | 258 | 1,135 | 738 | 7.69% | 2,221 | 0.5 | CDP |
| Dale | 259 | 1,116 | 699 | 7.62% | 470 | 2.4 | CDP |
| Gayle Mill | 260 | 1,110 | 832 | 1.28% | 1,695 | 0.7 | CDP |
| Dovesville | 261 | 1,106 | 1,101 | 7.69% | 158 | 7.0 | CDP |
| Yemassee | 262 | 1,077 | 1,095 | -0.46% | 99 | 10.9 | Town |
| Aynor | 263 | 1,074 | 982 | 2.19% | 596 | 1.8 | Town |
| Edisto Beach | 264 | 1,055 | 1,029 | 0.57% | 495 | 2.1 | Town |
| Pamplico | 265 | 1,052 | 1,060 | -0.19% | 649 | 1.6 | Town |
| Clifton | 266 | 1,032 | 691 | 3.51% | 962 | 1.1 | CDP |
| Van Wyck | 267 | 1,028 | 875 | 3.84% | 99 | 10.4 | Town |
| West Pelzer | 268 | 1,020 | 964 | 1.39% | 1,694 | 0.6 | Town |
| Sandy Springs | 269 | 1,018 | 974 | 7.61% | 354 | 2.9 | CDP |
| The Cliffs Valley | 270 | 982 | 663 | 7.67% | 152 | 6.5 | CDP |
| Fort Lawn | 271 | 975 | 965 | 0.21% | 700 | 1.4 | Town |
| Branchville | 272 | 965 | 987 | -0.62% | 305 | 3.2 | Town |
| Inman Mills | 273 | 940 | 801 | -0.84% | 871 | 1.1 | CDP |
| Pinopolis | 274 | 930 | 1,130 | -0.21% | 649 | 1.4 | CDP |
| Chesnee | 275 | 927 | 838 | 2.43% | 866 | 1.1 | City |
| Oakland | 276 | 912 | 1,265 | -2.46% | 1,341 | 0.7 | CDP |
| Quinby | 277 | 902 | 914 | -0.33% | 690 | 1.3 | Town |
| Newtown | 278 | 897 | 1,293 | 7.68% | 1,712 | 0.5 | CDP |
| Fripp Island | 279 | 895 | 848 | 7.7% | 274 | 3.3 | CDP |
| Hamer | 280 | 887 | 994 | 7.78% | 176 | 5.0 | CDP |
| Heath Springs | 281 | 859 | 749 | 3.25% | 529 | 1.6 | Town |
| Arcadia Lakes | 282 | 850 | 865 | -0.47% | 1,526 | 0.6 | Town |
| Lamar | 283 | 838 | 856 | -0.59% | 691 | 1.2 | Town |
| DeBordieu Colony | 284 | 812 | 712 | 7.69% | 197 | 4.1 | CDP |
| Jonesville | 285 | 811 | 849 | -1.22% | 799 | 1.0 | Town |
| Santee | 286 | 805 | 831 | -0.86% | 322 | 2.5 | Town |
| McBee | 287 | 792 | 770 | 0.64% | 603 | 1.3 | Town |
| Jefferson | 288 | 784 | 772 | 0.38% | 435 | 1.8 | Town |
| Summerton | 289 | 781 | 811 | -1.01% | 577 | 1.4 | Town |
| Gray Court | 290 | 779 | 769 | 0.26% | 411 | 1.9 | Town |
| Swansea | 291 | 771 | 726 | 1.45% | 369 | 2.1 | Town |
| Manville | 292 | 768 | 354 | 7.71% | 282 | 2.7 | CDP |
| Bowman | 293 | 760 | 780 | -0.65% | 646 | 1.2 | Town |
| Campobello | 294 | 757 | 681 | 2.57% | 272 | 2.8 | Town |
| Lake View | 295 | 757 | 787 | -1.05% | 444 | 1.7 | Town |
| Coward | 296 | 752 | 748 | 0.13% | 213 | 3.5 | Town |
| Six Mile | 297 | 752 | 758 | -0.27% | 369 | 2.0 | Town |
| Norris | 298 | 747 | 747 | 0% | 396 | 1.9 | Town |
| Pine Ridge | 299 | 747 | 704 | 7.79% | 329 | 2.3 | CDP |
| Turbeville | 300 | 741 | 761 | -0.67% | 553 | 1.3 | Town |
| Unity | 301 | 738 | 641 | 7.58% | 349 | 2.1 | CDP |
| Harleyville | 302 | 733 | 671 | 2.09% | 690 | 1.1 | Town |
| Bucksport | 303 | 722 | 607 | -1.5% | 172 | 4.2 | CDP |
| Cottageville | 304 | 714 | 701 | 0.42% | 209 | 3.4 | Town |
| Warrenville | 305 | 712 | 740 | -4.94% | 657 | 1.1 | CDP |
| Chickasaw Point | 306 | 704 | 532 | 7.81% | 322 | 2.2 | CDP |
| East Sumter | 307 | 697 | 1,208 | -6.19% | 210 | 3.3 | CDP |
| Wagener | 308 | 687 | 642 | 1.63% | 506 | 1.4 | Town |
| Fairview Crossroads | 309 | 686 | 665 | 7.69% | 120 | 5.7 | CDP |
| Centenary | 310 | 682 | 591 | 7.57% | 722 | 0.9 | CDP |
| North | 311 | 671 | 691 | -0.74% | 777 | 0.9 | Town |
| Modoc | 312 | 666 | 366 | 5.05% | 167 | 4.0 | CDP |
| Daufuskie Island | 313 | 664 | 485 | 7.79% | 68 | 9.8 | CDP |
| Scranton | 314 | 655 | 653 | 0% | 827 | 0.8 | Town |
| Elliott | 315 | 651 | 608 | 7.78% | 351 | 1.9 | CDP |
| Pelion | 316 | 624 | 627 | -0.16% | 169 | 3.7 | Town |
| Wallace | 317 | 624 | 713 | -2.96% | 95 | 6.6 | CDP |
| Eastover | 318 | 622 | 617 | 0.16% | 512 | 1.2 | Town |
| McClellanville | 319 | 622 | 606 | 0.65% | 279 | 2.2 | Town |
| Gilbert | 320 | 621 | 577 | 1.8% | 229 | 2.7 | Town |
| Little Rock | 321 | 612 | 848 | 7.56% | 249 | 2.5 | CDP |
| Buford | 322 | 610 | 708 | 7.58% | 268 | 2.3 | CDP |
| Finklea | 323 | 606 | 426 | 7.83% | 225 | 2.7 | CDP |
| Ridge Spring | 324 | 583 | 575 | 0.34% | 320 | 1.8 | Town |
| Clio | 325 | 574 | 604 | -1.38% | 671 | 0.9 | Town |
| Briarcliffe Acres | 326 | 565 | 484 | 3.67% | 888 | 0.6 | Town |
| Helena | 327 | 565 | 665 | 7.82% | 398 | 1.4 | CDP |
| Fair Play | 328 | 555 | 282 | -1.77% | 82 | 6.8 | CDP |
| Danwood | 329 | 548 | 361 | 7.66% | 289 | 1.9 | CDP |
| North Santee | 330 | 548 | 719 | 7.66% | 60 | 9.1 | CDP |
| Elloree | 331 | 544 | 567 | -1.09% | 512 | 1.1 | Town |
| Mayesville | 332 | 541 | 551 | -0.55% | 528 | 1.0 | Town |
| Olanta | 333 | 540 | 547 | -0.37% | 543 | 1.0 | Town |
| Adams Run | 334 | 522 | 772 | 7.85% | 371 | 1.4 | CDP |
| Sheldon | 335 | 512 | 501 | 7.56% | 117 | 4.4 | CDP |
| Startex | 336 | 502 | 556 | -4.92% | 453 | 1.1 | CDP |
| Pinewood | 337 | 497 | 503 | -0.4% | 464 | 1.1 | Town |
| Grover | 338 | 489 | 431 | 7.71% | 189 | 2.6 | CDP |
| Cash | 339 | 486 | 298 | 7.52% | 319 | 1.5 | CDP |
| Sharon | 340 | 467 | 461 | 0.21% | 356 | 1.3 | Town |
| Hickory Grove | 341 | 465 | 452 | 0.65% | 278 | 1.7 | Town |
| Hemingway | 342 | 462 | 500 | -2.12% | 535 | 0.9 | Town |
| Summit | 343 | 458 | 422 | 2% | 308 | 1.5 | Town |
| Lane | 344 | 448 | 472 | -1.32% | 113 | 4.0 | Town |
| South Union | 345 | 447 | 332 | 7.71% | 172 | 2.6 | CDP |
| Ehrhardt | 346 | 438 | 454 | -0.91% | 141 | 3.1 | Town |
| Bonneau | 347 | 436 | 428 | 0.46% | 144 | 3.0 | Town |
| Springfield | 348 | 430 | 448 | -1.15% | 247 | 1.7 | Town |
| Society Hill | 349 | 428 | 435 | -0.46% | 199 | 2.1 | Town |
| Hilda | 350 | 422 | 420 | 0% | 137 | 3.1 | Town |
| Cross Hill | 351 | 416 | 403 | 0.73% | 131 | 3.2 | Town |
| Brunson | 352 | 412 | 428 | -0.96% | 405 | 1.0 | Town |
| Oswego | 353 | 411 | 197 | 7.87% | 341 | 1.2 | CDP |
| Atlantic Beach | 354 | 406 | 200 | 14.37% | 2,506 | 0.2 | Town |
| Mount Carmel | 355 | 406 | 271 | 3.31% | 44 | 9.2 | CDP |
| Enoree | 356 | 404 | 560 | -4.26% | 261 | 1.5 | CDP |
| Cokesbury | 357 | 403 | 432 | 3.6% | 678 | 0.6 | CDP |
| West Union | 358 | 388 | 374 | 0.78% | 489 | 0.8 | Town |
| Alcolu | 359 | 378 | 413 | -0.79% | 83 | 4.5 | CDP |
| Gillisonville | 360 | 372 | 70 | 7.51% | 315 | 1.2 | CDP |
| Cameron | 361 | 369 | 375 | -0.54% | 118 | 3.1 | Town |
| Newry | 362 | 369 | 98 | 3.94% | 1,251 | 0.3 | CDP |
| Lockhart | 363 | 366 | 381 | -1.08% | 1,200 | 0.3 | Town |
| Greeleyville | 364 | 358 | 381 | -1.65% | 293 | 1.2 | Town |
| Salley | 365 | 353 | 335 | 1.15% | 461 | 0.8 | Town |
| Bethune | 366 | 336 | 316 | 1.51% | 305 | 1.1 | Town |
| Harbor Island | 367 | 323 | 316 | 7.67% | 315 | 1.0 | CDP |
| Donalds | 368 | 322 | 321 | 0% | 387 | 0.8 | Town |
| Ruby | 369 | 322 | 316 | 0.31% | 130 | 2.5 | Town |
| Carlisle | 370 | 313 | 319 | -0.64% | 221 | 1.4 | Town |
| Neeses | 371 | 311 | 319 | -0.64% | 182 | 1.7 | Town |
| Antreville | 372 | 310 | 203 | 4.03% | 80 | 3.9 | CDP |
| Promised Land | 373 | 304 | 555 | -4.7% | 195 | 1.6 | CDP |
| Lynchburg | 374 | 303 | 321 | -1.62% | 268 | 1.1 | Town |
| McConnells | 375 | 290 | 282 | 0.69% | 86 | 3.4 | Town |
| Daviston | 376 | 287 | 446 | 7.9% | 223 | 1.3 | CDP |
| Patrick | 377 | 283 | 273 | 0.71% | 295 | 1.0 | Town |
| Norway | 378 | 273 | 283 | -1.09% | 345 | 0.8 | Town |
| Richburg | 379 | 272 | 280 | -0.73% | 311 | 0.9 | Town |
| Pauline | 380 | 267 | 204 | 7.66% | 187 | 1.4 | CDP |
| Little Mountain | 381 | 260 | 251 | 0.78% | 171 | 1.5 | Town |
| Dacusville | 382 | 254 | 307 | 7.63% | 116 | 2.2 | CDP |
| Ridgeway | 383 | 252 | 266 | -1.56% | 520 | 0.5 | Town |
| Snelling | 384 | 250 | 250 | 0% | 62 | 4.0 | Town |
| Gifford | 385 | 248 | 258 | -1.2% | 256 | 1.0 | Town |
| Rembert | 386 | 246 | 219 | -1.99% | 64 | 3.8 | CDP |
| Glendale | 387 | 245 | 312 | -2% | 1,156 | 0.2 | CDP |
| Russellville | 388 | 245 | 173 | -6.84% | 65 | 3.7 | CDP |
| Rowesville | 389 | 244 | 250 | -0.81% | 293 | 0.8 | Town |
| Wisacky | 390 | 239 | 61 | 7.66% | 43 | 5.5 | CDP |
| Jacksonboro | 391 | 235 | 200 | -7.12% | 16 | 14.5 | CDP |
| Central Pacolet | 392 | 234 | 209 | 2.63% | 992 | 0.2 | Town |
| Eutawville | 393 | 234 | 237 | -0.43% | 246 | 1.0 | Town |
| Lobeco | 394 | 229 | 349 | 8.02% | 87 | 2.6 | CDP |
| Paxville | 395 | 228 | 231 | -0.44% | 217 | 1.1 | Town |
| Furman | 396 | 221 | 224 | -0.45% | 71 | 3.1 | Town |
| Nichols | 397 | 220 | 230 | -1.34% | 165 | 1.3 | Town |
| Glenn Springs | 398 | 218 | 231 | 7.39% | 98 | 2.2 | CDP |
| Trenton | 399 | 212 | 196 | 1.92% | 164 | 1.3 | Town |
| Perry | 400 | 210 | 194 | 1.94% | 219 | 1.0 | Town |
| Monetta | 401 | 206 | 197 | 0.98% | 299 | 0.7 | Town |
| Olar | 402 | 206 | 212 | -0.96% | 262 | 0.8 | Town |
| Reevesville | 403 | 192 | 202 | -1.54% | 119 | 1.6 | Town |
| Shiloh | 404 | 192 | 210 | -0.52% | 20 | 9.8 | CDP |
| Stuckey | 405 | 191 | 197 | -1.04% | 204 | 0.9 | Town |
| Lowrys | 406 | 182 | 185 | -0.55% | 58 | 3.2 | Town |
| Converse | 407 | 180 | 545 | -14.29% | 261 | 0.7 | CDP |
| Starr | 408 | 174 | 164 | 1.16% | 116 | 1.5 | Town |
| Silverstreet | 409 | 167 | 161 | 0.6% | 50 | 3.3 | Town |
| Hodges | 410 | 163 | 161 | 0% | 209 | 0.8 | Town |
| Bradley | 411 | 162 | 127 | 0% | 21 | 7.9 | CDP |
| Floydale | 412 | 162 | 278 | 7.29% | 80 | 2.0 | CDP |
| Lydia | 413 | 158 | 419 | -17.71% | 60 | 2.6 | CDP |
| Foreston | 414 | 155 | 124 | 7.64% | 68 | 2.3 | CDP |
| Waterloo | 415 | 155 | 151 | 0.65% | 87 | 1.8 | Town |
| Scotia | 416 | 154 | 160 | -1.28% | 49 | 3.2 | Town |
| Woodford | 417 | 153 | 159 | -1.29% | 195 | 0.8 | Town |
| Sellers | 418 | 145 | 148 | -0.69% | 217 | 0.7 | Town |
| Kline | 419 | 144 | 146 | -0.69% | 46 | 3.1 | Town |
| Elko | 420 | 141 | 140 | 0% | 134 | 1.0 | Town |
| Mountville | 421 | 140 | 75 | 2.19% | 49 | 2.9 | CDP |
| Rockville | 422 | 138 | 136 | 0% | 325 | 0.4 | Town |
| Pawleys Island | 423 | 136 | 131 | 0.74% | 194 | 0.7 | Town |
| Sycamore | 424 | 136 | 151 | -2.86% | 43 | 3.2 | Town |
| Mount Croghan | 425 | 133 | 132 | 0% | 175 | 0.8 | Town |
| Cordova | 426 | 131 | 138 | -1.5% | 300 | 0.4 | Town |
| Pomaria | 427 | 130 | 128 | 0% | 124 | 1.0 | Town |
| Parksville | 428 | 129 | 120 | 1.57% | 177 | 0.7 | Town |
| Livingston | 429 | 127 | 130 | -0.78% | 161 | 0.8 | Town |
| Mulberry | 430 | 126 | 207 | -18.71% | 64 | 2.0 | CDP |
| Salem | 431 | 124 | 120 | 0.81% | 136 | 0.9 | Town |
| Lowndesville | 432 | 123 | 122 | 0% | 159 | 0.8 | Town |
| Vance | 433 | 123 | 126 | -0.81% | 243 | 0.5 | Town |
| Windsor | 434 | 122 | 113 | 1.67% | 140 | 0.9 | Town |
| Ward | 435 | 120 | 120 | 0% | 155 | 0.8 | Town |
| Zion | 436 | 119 | 92 | 8.18% | 335 | 0.4 | CDP |
| Rains | 437 | 114 | 67 | 7.55% | 85 | 1.3 | CDP |
| Boykin | 438 | 110 | 119 | 0% | 16 | 6.9 | CDP |
| Blenheim | 439 | 108 | 114 | -1.82% | 165 | 0.7 | Town |
| Browntown | 440 | 105 | 106 | 7.14% | 43 | 2.5 | CDP |
| Smoaks | 441 | 97 | 99 | -1.02% | 60 | 1.6 | Town |
| Tamassee | 442 | 96 | 149 | 7.87% | 82 | 1.2 | CDP |
| Williams | 443 | 95 | 97 | -1.04% | 112 | 0.8 | Town |
| Luray | 444 | 94 | 97 | -1.05% | 91 | 1.0 | Town |
| Fingerville | 445 | 93 | 31 | -3.13% | 381 | 0.2 | CDP |
| Gramling | 446 | 92 | 97 | 6.98% | 92 | 1.0 | CDP |
| Princeton | 447 | 91 | 60 | 8.33% | 117 | 0.8 | CDP |
| St. Charles | 448 | 88 | 71 | 8.64% | 21 | 4.2 | CDP |
| Troy | 449 | 87 | 85 | 0% | 109 | 0.8 | Town |
| Plum Branch | 450 | 83 | 79 | 1.22% | 112 | 0.7 | Town |
| Lodge | 451 | 81 | 83 | -1.22% | 26 | 3.1 | Town |
| Tradesville | 452 | 78 | 90 | 6.85% | 39 | 2.0 | CDP |
| Ashwood | 453 | 74 | 57 | 8.82% | 21 | 3.6 | CDP |
| Green Sea | 454 | 74 | 70 | 8.82% | 42 | 1.8 | CDP |
| Ware Place | 455 | 74 | 116 | -12.94% | 81 | 0.9 | CDP |
| Jamestown | 456 | 71 | 71 | 0% | 117 | 0.6 | Town |
| Tatum | 457 | 70 | 74 | -1.41% | 77 | 0.9 | Town |
| Willington | 458 | 70 | 0 | -6.67% | 12 | 6.0 | CDP |
| Smyrna | 459 | 57 | 57 | 0% | 81 | 0.7 | Town |
| Ulmer | 460 | 57 | 64 | -3.39% | 21 | 2.7 | Town |
| Peak | 461 | 55 | 51 | 1.85% | 160 | 0.3 | Town |
| Govan | 462 | 51 | 54 | -1.92% | 68 | 0.8 | Town |
| Caesars Head | 463 | 49 | 53 | 6.52% | 33 | 1.5 | CDP |
| Islandton | 464 | 47 | 49 | 9.3% | 17 | 2.8 | CDP |
| Jenkinsville | 465 | 39 | 41 | -2.5% | 438 | 0.1 | Town |
| Cherokee Falls | 466 | 35 | 0 | 9.38% | 307 | 0.1 | CDP |
| Longcreek | 467 | 34 | 36 | 9.68% | 18 | 1.9 | CDP |
| Cope | 468 | 31 | 33 | -3.13% | 124 | 0.3 | Town |
| Clarks Hill | 469 | 28 | 195 | -47.17% | 9 | 3.2 | CDP |
| Abney Crossroads | 470 | 24 | 110 | 4.35% | 53 | 0.5 | CDP |
| Coosawhatchie | 471 | 12 | 0 | 9.09% | 20 | 0.6 | CDP |
| Live Oak | 472 | 10 | 66 | 0% | 12 | 0.8 | CDP |
| Cross Anchor | 473 | 8 | 70 | -52.94% | 10 | 0.8 | CDP |
| Coronaca | 474 | 6 | 81 | -68.42% | 4 | 1.7 | CDP |
| Ketchuptown | 475 | 6 | 35 | 20% | 2 | 2.7 | CDP |
With over 5 million residents, South Carolina is the 23rd most populous state in the country. The state has three cities that have populations exceeding 100,000. The most populous city is the capital, Columbia, which has a population of 133,803 per 2017 estimates. Charleston follows closely behind with 132,609 inhabitants. The third city, North Charleston, has a population of 108,304. The state has 35 cities with populations of at least 10,000.
Incorporated municipalities in South Carolina are designated as cities or towns, and there is a total of 269 across 46 counties. There is no legal difference between cities and towns in this state. The smallest incorporated area is Smyrna located in the counties of Cherokee and York, and has just 45 inhabitants and is classified as a town. The smallest classified city in South Carolina is Chesnee and Cherokee and Spartanburg Counties. This city has a population of just 838 residents.
Charleston is the biggest city in South Carolina, with a population of 156,868 in 2024.
Hardeeville is the fastest growing city in South Carolina over the past 4 years, having grown 11.69% annually since 2020.
The 10 largest cities in South Carolina are: Charleston, Columbia, North Charleston, Mount Pleasant, Rock Hill, Greenville, Summerville, Goose Creek, Greer and Sumter.