| City | Rank | Annual Change ↓ | 2026 Pop. | 2020 Pop. |
|---|---|---|---|---|
| Hardeeville | 1 | 9.74% | 18,062 | 7,764 |
| Fort Mill | 2 | 7.12% | 41,426 | 25,195 |
| Blythewood | 3 | 6.46% | 7,700 | 4,852 |
| Moncks Corner | 4 | 6.13% | 21,875 | 13,440 |
| Fountain Inn | 5 | 5.63% | 15,551 | 10,511 |
| Bluffton | 6 | 5.48% | 38,825 | 28,300 |
| Greer | 7 | 5.34% | 52,676 | 35,916 |
| Simpsonville | 8 | 4.05% | 29,612 | 23,633 |
| Mauldin | 9 | 4.05% | 32,739 | 24,808 |
| Conway | 10 | 3.73% | 31,769 | 25,210 |
| Easley | 11 | 3.6% | 28,302 | 23,040 |
| Woodruff | 12 | 3.5% | 6,237 | 4,311 |
| Travelers Rest | 13 | 3.21% | 9,428 | 7,821 |
| Kershaw | 14 | 3.19% | 2,103 | 1,729 |
| Loris | 15 | 3.13% | 3,027 | 2,467 |
| Camden | 16 | 3.12% | 9,488 | 7,802 |
| York | 17 | 2.99% | 10,938 | 8,561 |
| Port Royal | 18 | 2.99% | 17,145 | 14,757 |
| Myrtle Beach | 19 | 2.87% | 42,111 | 35,972 |
| Reidville | 20 | 2.78% | 1,958 | 1,640 |
| Lyman | 21 | 2.72% | 7,296 | 6,140 |
| Duncan | 22 | 2.72% | 4,802 | 4,044 |
| Wellford | 23 | 2.71% | 4,020 | 3,386 |
| Landrum | 24 | 2.69% | 2,942 | 2,480 |
| Pacolet | 25 | 2.69% | 2,715 | 2,285 |
| Inman | 26 | 2.66% | 3,550 | 2,998 |
| Clover | 27 | 2.52% | 7,852 | 6,786 |
| Tega Cay | 28 | 2.41% | 14,805 | 12,867 |
| Cowpens | 29 | 2.3% | 2,309 | 2,030 |
| North Myrtle Beach | 30 | 2.25% | 21,826 | 18,940 |
| Lancaster | 31 | 2.19% | 9,834 | 8,502 |
| Johnston | 32 | 2.15% | 2,281 | 1,999 |
| North Charleston | 33 | 2.12% | 131,980 | 115,610 |
| Goose Creek | 34 | 2.11% | 53,108 | 46,335 |
| Hanahan | 35 | 1.77% | 22,812 | 20,580 |
| North Augusta | 36 | 1.66% | 27,429 | 24,473 |
| Lexington | 37 | 1.66% | 26,155 | 23,720 |
| Pine Ridge | 38 | 1.53% | 2,382 | 2,173 |
| Chapin | 39 | 1.49% | 1,974 | 1,808 |
| Jackson | 40 | 1.46% | 1,663 | 1,528 |
| Columbia | 41 | 1.41% | 149,103 | 135,860 |
| Pendleton | 42 | 1.36% | 3,790 | 3,498 |
| Honea Path | 43 | 1.34% | 4,003 | 3,696 |
| Edgefield | 44 | 1.34% | 4,238 | 3,910 |
| Williamston | 45 | 1.34% | 4,396 | 4,060 |
| Pelzer | 46 | 1.32% | 1,453 | 1,346 |
| Iva | 47 | 1.32% | 1,225 | 1,132 |
| Georgetown | 48 | 1.32% | 8,986 | 8,386 |
| Belton | 49 | 1.32% | 4,692 | 4,341 |
| Burnettown | 50 | 1.32% | 3,310 | 3,070 |
| Lincolnville | 51 | 1.29% | 1,257 | 1,156 |
| West Columbia | 52 | 1.28% | 18,726 | 17,489 |
| Beaufort | 53 | 1.26% | 15,974 | 13,721 |
| Surfside Beach | 54 | 1.25% | 4,447 | 4,162 |
| Anderson | 55 | 1.25% | 31,715 | 29,506 |
| Mount Pleasant | 56 | 1.24% | 96,654 | 91,244 |
| New Ellenton | 57 | 1.24% | 2,367 | 2,203 |
| Due West | 58 | 1.23% | 1,315 | 1,230 |
| Irmo | 59 | 1.22% | 12,353 | 11,511 |
| Ravenel | 60 | 1.21% | 2,761 | 2,551 |
| Prosperity | 61 | 1.19% | 1,274 | 1,182 |
| Charleston | 62 | 1.19% | 161,314 | 151,225 |
| Hollywood | 63 | 1.17% | 5,718 | 5,301 |
| Greenville | 64 | 1.16% | 76,180 | 71,465 |
| Awendaw | 65 | 1.13% | 1,519 | 1,410 |
| Clemson | 66 | 1.1% | 19,149 | 17,758 |
| Meggett | 67 | 1.08% | 1,500 | 1,396 |
| Walhalla | 68 | 1.06% | 4,366 | 4,084 |
| Seabrook Island | 69 | 0.97% | 2,192 | 2,055 |
| Seneca | 70 | 0.97% | 9,515 | 8,851 |
| Westminster | 71 | 0.96% | 2,528 | 2,375 |
| James Island | 72 | 0.96% | 12,781 | 12,014 |
| Whitmire | 73 | 0.95% | 1,489 | 1,406 |
| Blacksburg | 74 | 0.87% | 1,982 | 1,887 |
| Edisto Beach | 75 | 0.84% | 1,080 | 1,029 |
| Summerville | 76 | 0.84% | 53,623 | 50,944 |
| Sullivan's Island | 77 | 0.76% | 1,976 | 1,898 |
| Spartanburg | 78 | 0.71% | 40,261 | 38,606 |
| Clinton | 79 | 0.68% | 7,972 | 7,628 |
| Florence | 80 | 0.58% | 41,470 | 39,969 |
| Pageland | 81 | 0.56% | 2,532 | 2,465 |
| St. Stephen | 82 | 0.55% | 1,632 | 1,579 |
| Hilton Head Island | 83 | 0.54% | 38,403 | 37,592 |
| Calhoun Falls | 84 | 0.51% | 1,788 | 1,727 |
| Newberry | 85 | 0.49% | 10,944 | 10,704 |
| Elgin | 86 | 0.48% | 1,683 | 1,633 |
| Orangeburg | 87 | 0.43% | 13,441 | 13,174 |
| Gaston | 88 | 0.42% | 1,658 | 1,616 |
| Batesburg-Leesville | 89 | 0.39% | 5,367 | 5,259 |
| Rock Hill | 90 | 0.38% | 76,202 | 74,631 |
| St. George | 91 | 0.37% | 1,875 | 1,833 |
| Ware Shoals | 92 | 0.35% | 1,739 | 1,703 |
| Chesterfield | 93 | 0.29% | 1,361 | 1,344 |
| Ridgeland | 94 | 0.29% | 3,829 | 3,745 |
| Timmonsville | 95 | 0.28% | 2,123 | 2,094 |
| Aiken | 96 | 0.27% | 33,899 | 32,180 |
| Isle of Palms | 97 | 0.25% | 4,388 | 4,348 |
| Greenwood | 98 | 0.22% | 22,796 | 22,503 |
| Springdale | 99 | 0.21% | 2,883 | 2,738 |
| Central | 100 | 0.21% | 5,309 | 5,298 |
| Folly Beach | 101 | 0.19% | 2,085 | 2,074 |
| Pickens | 102 | 0.19% | 3,194 | 3,145 |
| Yemassee | 103 | 0.17% | 1,147 | 1,130 |
| Abbeville | 104 | 0.16% | 4,910 | 4,843 |
| Ninety Six | 105 | 0.14% | 2,092 | 2,076 |
| Pamplico | 106 | 0.09% | 1,063 | 1,060 |
| Walterboro | 107 | 0.05% | 5,488 | 5,495 |
| Saluda | 108 | 0% | 3,086 | 3,080 |
| South Congaree | 109 | 0% | 2,424 | 2,422 |
| Laurens | 110 | -0.01% | 9,326 | 9,342 |
| Chester | 111 | -0.04% | 5,322 | 5,271 |
| Kiawah Island | 112 | -0.05% | 2,013 | 2,015 |
| Johnsonville | 113 | -0.07% | 1,347 | 1,358 |
| Great Falls | 114 | -0.1% | 1,958 | 1,947 |
| Williston | 115 | -0.1% | 2,895 | 2,890 |
| Cayce | 116 | -0.12% | 13,664 | 13,778 |
| Hartsville | 117 | -0.16% | 7,362 | 7,439 |
| Blackville | 118 | -0.21% | 1,921 | 1,927 |
| Sumter | 119 | -0.23% | 42,995 | 43,451 |
| Liberty | 120 | -0.24% | 3,336 | 3,391 |
| St. Matthews | 121 | -0.27% | 1,822 | 1,849 |
| Barnwell | 122 | -0.28% | 4,606 | 4,648 |
| Cheraw | 123 | -0.3% | 4,906 | 4,999 |
| Andrews | 124 | -0.36% | 2,513 | 2,588 |
| Gaffney | 125 | -0.36% | 12,538 | 12,722 |
| Manning | 126 | -0.39% | 3,814 | 3,904 |
| Lake City | 127 | -0.4% | 5,916 | 6,025 |
| Forest Acres | 128 | -0.4% | 10,348 | 10,629 |
| Darlington | 129 | -0.44% | 6,048 | 6,201 |
| Estill | 130 | -0.45% | 1,770 | 1,812 |
| Union | 131 | -0.54% | 8,033 | 8,211 |
| Holly Hill | 132 | -0.63% | 1,272 | 1,313 |
| Winnsboro | 133 | -0.7% | 3,282 | 3,424 |
| Denmark | 134 | -0.78% | 3,035 | 3,167 |
| Varnville | 135 | -0.8% | 1,613 | 1,680 |
| Mullins | 136 | -0.86% | 3,805 | 4,015 |
| Hampton | 137 | -0.96% | 2,573 | 2,708 |
| Dillon | 138 | -0.96% | 6,167 | 6,519 |
| Marion | 139 | -1.05% | 5,965 | 6,370 |
| Latta | 140 | -1.05% | 1,222 | 1,296 |
| Bishopville | 141 | -1.06% | 2,799 | 2,993 |
| McColl | 142 | -1.06% | 1,953 | 2,061 |
| Bamberg | 143 | -1.1% | 2,888 | 3,060 |
| Bennettsville | 144 | -1.16% | 7,477 | 7,957 |
| Kingstree | 145 | -1.46% | 2,978 | 3,230 |
| Allendale | 146 | -1.9% | 2,381 | 2,680 |
| Fairfax | 147 | -1.92% | 1,326 | 1,485 |
| McCormick | 148 | -3.13% | 1,947 | 2,226 |
| Ridgeville | 149 | -12.2% | 1,080 | 1,832 |
South Carolina's cities with over 1,000 residents show varied growth patterns from 2020 to 2025. Hardeeville leads with 9.74% annualized growth, followed by Fort Mill (7.12%) and Blythewood (6.46%). The largest population centers are Charleston (161,314), Columbia (149,103), and North Charleston (131,980). Of the 149 cities over 1,000 population, 109 are growing while 40 experienced population decline. Overall, cities averaged 0.99% annualized growth, with total urban population growing by 11.35% annually.