148 cities
| City | Rank | Annual Change ↓ | 2026 Pop. | 2020 Pop. |
|---|---|---|---|---|
| Hardeeville | 1 | 9.95% | 16,926 | 7,733 |
| Fort Mill | 2 | 7.08% | 41,764 | 25,204 |
| Blythewood | 3 | 6.5% | 7,669 | 4,860 |
| Moncks Corner | 4 | 6.27% | 20,817 | 13,443 |
| Fountain Inn | 5 | 5.61% | 15,423 | 10,512 |
| Greer | 6 | 5.36% | 51,559 | 35,829 |
| Bluffton | 7 | 5.13% | 40,057 | 28,324 |
| Mauldin | 8 | 4% | 32,226 | 24,786 |
| Woodruff | 9 | 3.96% | 5,489 | 4,237 |
| Simpsonville | 10 | 3.83% | 30,314 | 23,605 |
| Conway | 11 | 3.64% | 31,896 | 25,176 |
| Easley | 12 | 3.54% | 28,984 | 23,034 |
| Kershaw | 13 | 3.22% | 2,147 | 1,748 |
| York | 14 | 3.14% | 10,467 | 8,556 |
| Loris | 15 | 3.09% | 3,005 | 2,465 |
| Travelers Rest | 16 | 3.08% | 9,530 | 7,819 |
| Camden | 17 | 2.99% | 9,446 | 7,804 |
| Port Royal | 18 | 2.84% | 17,470 | 14,581 |
| Duncan | 19 | 2.77% | 4,856 | 4,070 |
| Myrtle Beach | 20 | 2.74% | 42,816 | 35,973 |
| Reidville | 21 | 2.7% | 1,943 | 1,640 |
| Pacolet | 22 | 2.66% | 2,705 | 2,288 |
| Landrum | 23 | 2.62% | 2,942 | 2,491 |
| Inman | 24 | 2.59% | 3,531 | 3,000 |
| Lyman | 25 | 2.58% | 7,306 | 6,205 |
| Wellford | 26 | 2.58% | 3,931 | 3,337 |
| Clover | 27 | 2.52% | 7,947 | 6,780 |
| Tega Cay | 28 | 2.42% | 15,001 | 12,880 |
| Johnston | 29 | 2.34% | 2,320 | 2,001 |
| Lancaster | 30 | 2.27% | 9,832 | 8,523 |
| North Myrtle Beach | 31 | 2.21% | 21,735 | 18,924 |
| Cowpens | 32 | 2.19% | 2,329 | 2,032 |
| North Charleston | 33 | 2.02% | 131,201 | 115,613 |
| Goose Creek | 34 | 1.99% | 52,398 | 46,260 |
| North Augusta | 35 | 1.78% | 27,349 | 24,486 |
| Lexington | 36 | 1.65% | 26,204 | 23,653 |
| Jackson | 37 | 1.62% | 1,689 | 1,527 |
| Hanahan | 38 | 1.57% | 22,684 | 20,580 |
| Pine Ridge | 39 | 1.57% | 2,399 | 2,179 |
| Chapin | 40 | 1.53% | 1,993 | 1,816 |
| New Ellenton | 41 | 1.47% | 2,423 | 2,216 |
| Columbia | 42 | 1.46% | 149,078 | 136,207 |
| Pelzer | 43 | 1.45% | 1,470 | 1,346 |
| Edgefield | 44 | 1.4% | 4,265 | 3,910 |
| Pendleton | 45 | 1.33% | 3,797 | 3,497 |
| Iva | 46 | 1.33% | 1,222 | 1,128 |
| Burnettown | 47 | 1.32% | 3,312 | 3,054 |
| Williamston | 48 | 1.31% | 4,399 | 4,056 |
| Belton | 49 | 1.25% | 4,688 | 4,343 |
| Ravenel | 50 | 1.25% | 2,756 | 2,552 |
| Georgetown | 51 | 1.23% | 9,041 | 8,381 |
| Honea Path | 52 | 1.22% | 3,981 | 3,693 |
| Beaufort | 53 | 1.22% | 14,688 | 13,625 |
| Irmo | 54 | 1.22% | 12,383 | 11,491 |
| West Columbia | 55 | 1.21% | 18,869 | 17,516 |
| Anderson | 56 | 1.18% | 31,676 | 29,458 |
| Surfside Beach | 57 | 1.18% | 4,472 | 4,160 |
| Due West | 58 | 1.15% | 1,322 | 1,231 |
| Lincolnville | 59 | 1.14% | 1,240 | 1,156 |
| Clemson | 60 | 1.14% | 19,037 | 17,755 |
| Mount Pleasant | 61 | 1.13% | 97,780 | 91,251 |
| Prosperity | 62 | 1.11% | 1,272 | 1,187 |
| Awendaw | 63 | 1.08% | 1,503 | 1,409 |
| Charleston | 64 | 1.04% | 160,965 | 151,065 |
| Meggett | 65 | 1.02% | 1,482 | 1,394 |
| Walhalla | 66 | 1% | 4,334 | 4,079 |
| Greenville | 67 | 0.98% | 75,842 | 71,428 |
| Hollywood | 68 | 0.94% | 5,607 | 5,294 |
| Seabrook Island | 69 | 0.93% | 2,175 | 2,055 |
| Seneca | 70 | 0.93% | 9,373 | 8,860 |
| Blacksburg | 71 | 0.86% | 1,987 | 1,888 |
| James Island | 72 | 0.86% | 12,666 | 12,020 |
| Westminster | 73 | 0.85% | 2,481 | 2,354 |
| Summerville | 74 | 0.79% | 53,459 | 50,957 |
| Whitmire | 75 | 0.76% | 1,461 | 1,394 |
| Edisto Beach | 76 | 0.75% | 1,076 | 1,028 |
| Clinton | 77 | 0.71% | 7,964 | 7,627 |
| Sullivan's Island | 78 | 0.66% | 1,974 | 1,896 |
| Spartanburg | 79 | 0.63% | 40,107 | 38,604 |
| Gaston | 80 | 0.55% | 1,658 | 1,606 |
| Pageland | 81 | 0.51% | 2,548 | 2,470 |
| Florence | 82 | 0.5% | 41,336 | 40,096 |
| Newberry | 83 | 0.41% | 10,963 | 10,696 |
| Aiken | 84 | 0.41% | 32,962 | 32,158 |
| Rock Hill | 85 | 0.38% | 76,370 | 74,654 |
| Hilton Head Island | 86 | 0.37% | 38,444 | 37,586 |
| Orangeburg | 87 | 0.37% | 13,478 | 13,178 |
| Elgin | 88 | 0.36% | 1,669 | 1,632 |
| Central | 89 | 0.32% | 5,373 | 5,270 |
| St. Stephen | 90 | 0.31% | 1,602 | 1,571 |
| Chesterfield | 91 | 0.3% | 1,359 | 1,335 |
| Calhoun Falls | 92 | 0.29% | 1,757 | 1,727 |
| Pickens | 93 | 0.28% | 3,206 | 3,151 |
| Batesburg-Leesville | 94 | 0.26% | 5,348 | 5,267 |
| Timmonsville | 95 | 0.24% | 2,126 | 2,098 |
| St. George | 96 | 0.22% | 1,863 | 1,838 |
| Ware Shoals | 97 | 0.17% | 1,722 | 1,704 |
| Isle of Palms | 98 | 0.16% | 4,391 | 4,348 |
| Springdale | 99 | 0.14% | 2,764 | 2,740 |
| Greenwood | 100 | 0.12% | 22,721 | 22,558 |
| Folly Beach | 101 | 0.1% | 2,088 | 2,076 |
| South Congaree | 102 | 0.08% | 2,396 | 2,384 |
| Abbeville | 103 | 0.06% | 4,876 | 4,857 |
| Ninety Six | 104 | 0% | 2,075 | 2,074 |
| Pamplico | 105 | 0% | 1,061 | 1,060 |
| Yemassee | 106 | 0% | 1,127 | 1,126 |
| Laurens | 107 | -0.03% | 9,345 | 9,365 |
| Ridgeland | 108 | -0.05% | 3,739 | 3,753 |
| Walterboro | 109 | -0.07% | 5,480 | 5,503 |
| Johnsonville | 110 | -0.07% | 1,347 | 1,356 |
| Williston | 111 | -0.14% | 2,871 | 2,895 |
| Kiawah Island | 112 | -0.15% | 1,997 | 2,014 |
| Saluda | 113 | -0.16% | 3,051 | 3,080 |
| Chester | 114 | -0.19% | 5,209 | 5,272 |
| Cayce | 115 | -0.21% | 13,589 | 13,756 |
| St. Matthews | 116 | -0.22% | 1,826 | 1,849 |
| Hartsville | 117 | -0.26% | 7,321 | 7,438 |
| Great Falls | 118 | -0.26% | 1,915 | 1,948 |
| Blackville | 119 | -0.26% | 1,896 | 1,925 |
| Cheraw | 120 | -0.26% | 4,919 | 5,000 |
| Liberty | 121 | -0.27% | 3,333 | 3,389 |
| Sumter | 122 | -0.28% | 42,714 | 43,445 |
| Barnwell | 123 | -0.33% | 4,558 | 4,650 |
| Gaffney | 124 | -0.38% | 12,450 | 12,738 |
| Forest Acres | 125 | -0.44% | 10,346 | 10,621 |
| Manning | 126 | -0.47% | 3,795 | 3,905 |
| Lake City | 127 | -0.48% | 5,859 | 6,030 |
| Estill | 128 | -0.57% | 1,749 | 1,811 |
| Andrews | 129 | -0.6% | 2,500 | 2,590 |
| Darlington | 130 | -0.6% | 5,972 | 6,190 |
| Holly Hill | 131 | -0.64% | 1,242 | 1,292 |
| Union | 132 | -0.72% | 7,874 | 8,215 |
| Varnville | 133 | -0.74% | 1,605 | 1,680 |
| Denmark | 134 | -0.82% | 3,022 | 3,172 |
| Winnsboro | 135 | -0.86% | 3,222 | 3,393 |
| Hampton | 136 | -0.97% | 2,552 | 2,702 |
| Bishopville | 137 | -0.98% | 2,823 | 2,993 |
| Bamberg | 138 | -1% | 2,885 | 3,058 |
| Dillon | 139 | -1.05% | 6,113 | 6,506 |
| Latta | 140 | -1.06% | 1,215 | 1,295 |
| Mullins | 141 | -1.08% | 3,764 | 4,009 |
| McColl | 142 | -1.18% | 1,930 | 2,067 |
| Marion | 143 | -1.25% | 5,918 | 6,368 |
| Bennettsville | 144 | -1.31% | 7,398 | 7,989 |
| Kingstree | 145 | -1.43% | 2,968 | 3,228 |
| Fairfax | 146 | -1.76% | 1,340 | 1,487 |
| Allendale | 147 | -1.88% | 2,403 | 2,681 |
| McCormick | 148 | -3.48% | 1,828 | 2,223 |
South Carolina's cities with over 1,000 residents show varied growth patterns from 2020 to 2025. Hardeeville leads with 9.95% annualized growth, followed by Fort Mill (7.08%) and Blythewood (6.5%). The largest population centers are Charleston (160,965), Columbia (149,078), and North Charleston (131,201). Of the 148 cities over 1,000 population, 106 are growing while 42 experienced population decline. Overall, cities averaged 1.03% annualized growth, with total urban population growing by 11.06% annually.