Cayce
- County:
- Lexington County
- County Seat:
- No
- Area (mi²):
- 16.881
- State:
- South Carolina
Cayce is a city located in Lexington County, South Carolina. Cayce has a 2026 population of 13,645. Cayce is currently declining at a rate of -0.29% annually and its population has decreased by -0.81% since the most recent census, which recorded a population of 13,756 in 2020.