Vance
- County:
- Orangeburg County
- County Seat:
- No
- Area (mi²):
- 0.507
- State:
- South Carolina
Vance is a town located in Orangeburg County, South Carolina. Vance has a 2026 population of 124. Vance is currently declining at a rate of -0.8% annually and its population has decreased by -2.36% since the most recent census, which recorded a population of 127 in 2020.