| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Bluffton | 1 | 38,825 | 28,300 | 5.48% | 745 | 52 | Town |
| Hilton Head Island | 2 | 38,403 | 37,592 | 0.54% | 929 | 41 | Town |
| Port Royal | 3 | 17,145 | 14,757 | 2.99% | 888 | 19 | Town |
| Beaufort | 4 | 15,974 | 13,721 | 1.26% | 654 | 24 | City |
Bluffton is the largest city in Beaufort County, with a population of 38,825.
Beaufort is the smallest city in Beaufort County, with a population of 15,974.
There are 4 cities in Beaufort County, South Carolina.